The Southern Medical Journal (SMJ) is the official, peer-reviewed journal of the Southern Medical Association. It has a multidisciplinary and inter-professional focus that covers a broad range of topics relevant to physicians and other healthcare specialists.

SMJ // Article

Letter to the Editor

Cryptococcosis in Sarcoidosis

Authors: Isabelle Marie, MD, PhD, Sarah Cheriet, MD, Cyrielle Assie, MD, Manuel Etienne, MD, Loïc Favennec, MD, PhD

Abstract

To the Editor:


Sarcoidosis is an immune-mediated condition affecting multiple organs, especially the lungs, lymph nodes, skin, and eyes. Infections are considered to be a rare complication of sarcoidosis; in two retrospective clinical series of 122 and 197 patients with sarcoidosis, infections have been reported in 2.5% and 0% of cases, respectively.1,2 We recently observed the interesting case of a patient with sarcoidosis who developed cutaneous and meningeal cryptococcal infection.

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References

1. Rubinstein I, Baum GL, Rosenthal T. Fungal infections complicating pulmonary sarcoidosis. J Infect Dis 1985;152:1360.
 
2. Winterbauer RH, Kraemer KG. The infectious complications of sarcoidosis: a current perspective. Arch Intern Med 1976;136:1356-1362.
 
3. Dhote R, Abad S, Valeyre D. Complications infectieuses de la sarcoïdose. Presse Med 2009;38:317-323.
 
4. Baughman RP, Lower EE. Fungal infections as a complication of therapy for sarcoidosis. QJM 2005;98:451-456.
 
5. Arnaud L, Sene D, Costedoat-Chalumeau N, et al. Disseminated crytococcal infection and anti-tumor necrosing factor-α treatment for refractory sarcoidosis: an expected association? J Rheumatol 2009;36:462.
 
6. Blanchon F, Vannier R, Brunel D, et al. [Cutaneous, subcutaneous, and lymph node cryptococcosis in a patient with sarcoidosis.] Ann Med interne (Paris) 1979;130:455-458.
 
 
7. Bohne T, Sander A, Pfister-Wartha A, et al. Primary cutaneous cryptococcosis following trauma of the right forearm. Mycoses 1996;39:457-459.
 
8.Lauerma AI, Jeskanen L, Rantanen T, et al. Cryptococcosis during systemic glucosteroid treatment. Dermatology 1999;199:180-182.
 
 
9. Mehrany K, Kist JM, Gibson LE. Cryptococcal infection in sarcoidosis. Int J Dermatol 2002;41:773-774.
 
10. Riha RL, Allen RK. Cryptocococcosis and sarciodosis: strange bed-fellows. A report of five cases. Sarcoidosis Vasc Diffuse Lung Dis 2004;21:71-76.