Cutaneous Complications of Parenteral Pentazocine
AbstractAbstract: Two men who had received parenteral pentazocine in large doses for years developed severe chronic cutaneous complications. Skin changes included brawny thickening around the site of injections and large, deep penetrating ulcers. Sclerosis of the skin and subcutaneous tissue became generalized in one patient, resulting in marked immobility of the thorax and extremities and consequent total disability. These changes thus far have been seen only in abusers of pentazocine, and, once developed, may be irreversible.
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