Review Article

Henoch-Schönlein Purpura: A Review Article

Authors: Paul F. Roberts, MD, Thomas A. Waller, MD, Todd M. Brinker, MD, Izabela Z. Riffe, MD, Jerry W. Sayre, MD, Robert L. Bratton, MD


Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood. Although HSP is typically a disease of children, adult cases have been described. HSP can affect multiple organs with a characteristic rash present in all patients. Most cases resolve with symptomatic treatment, but serious complications can occur such as renal failure. Primary care physicians should be well aware of the disease because the true incidence is probably underestimated.

Key Points

* Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood.

* HSP can affect multiple organs, with a rash present in all cases.

* Treatment of HSP is usually symptomatic, but serious complications can occur.

* The true incidence of HSP is probably underestimated.

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