Book Review

Induction of Labor With Prostaglandin E2 Administered Orally

Authors: FRANK H. BOEHM MD, S. JANE HODGE RN, FAYE H. SHAFFER RN

Abstract

ABSTRACTThe effectiveness of orally administered prostagiandin E., in inducing labor was studied in 60 patients with uncomplicated, full-term pregnancies, using three dosage schedules. Although 40 patients did deliver, 11 patients' amniotic membranes ruptured at a time considered by the investigators to introduce an undesired variable in attempting to evaluate the drug. Twenty (33%) failed to deliver despite adequate Bishop scores. Side effects were noted in 45% of patients. No significant advantage for induction of labor occurred with the three dosage schedules used.

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