Case Report

Rapid Development of an Axillary Mass in an Adult: A Case of Cystic Hygroma

Authors: Othon Michail, MD, Panagiotis Michail, MD, PhD, Despoina Kyriaki, MD, PhD, Anna Kolindou, MD, Chris Klonaris, MD, PhD, John Griniatsos, MD, PhD


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1. Cheng LH, Wells FC. A multidisciplinary approach to recurrent cervicothoracic cystic hygroma in an adult. Br J Oral Maxillofac Surg 2004;42:66–68.
2. Coffin CM, Dehner LP. Vascular tumors in children and adolescents: a clinicopathologic study of 228 tumors in 222 patients. Pathol Annu 1993;28(Pt 1):97–120.
3. Torcasio A, Veneroso S, Amabile MI, et al. Cystic hygroma of the breast: a rare lesion. Tumori2006;92:347–350.
4. Sarin YK. Cystic hygroma. Indian Pediatr 2000;37:1139–1140.
5. Suk S, Sheridan M, Saenger JS. Adult lymphangioma: a case report. Ear Nose Throat J1997;76:881–883.
6. Brown LR, Reiman HM, Rosenow EC III, et al. Intrathoracic lymphangioma. Mayo Clin Proc1986;61:882–892.
7. Feutz EP, Yune HY, Mandelbaum I, et al. Intrathoracic cystic hygroma: a report of three cases.Radiology 1973;108:61–66.
8. Aneeshkumar MK, Kale S, Kabbani M, et al. Cystic lymphangioma in adults: can trauma be the trigger? Eur Arch Otorhinolaryngol 2005;262:335–337.
9. Wever DJ, Heeg M, Mooyaart EL. Cystic hygroma of the shoulder region: a case report. Clin Orthop Relat Res 1997;338:215–218.
10. Poyraz AS, Kilic D, Hatipoglu A, et al. Cystic lymphangioma confined to mediastinum in an adult.Jpn J Thorac Cardiovasc Surg 2004;52:567–569.
11. Guinier D, Denue PO, Mantion GA. Intra-abdominal cystic lymphangioma. Am J Surg2006;191:706–707.
12. Solomou EG, Patriarheas GV, Mpadra FA, et al. Asymptomatic adult cystic lymphangioma of the spleen: case report and review of the literature. Magn Reson Imaging 2003;21:81–84.
13. Cherk M, Nikfarjam M, Christophi C. Retroperitoneal lymphangioma. Asian J Surg 2006;29:51–54.
14. Erdem S, Iskender C, Avsar AF, et al. Benign cystic lymphangioma presenting as a pelvic mass. J Obstet Gynaecol Res 2006;32:628–630.
15. Smith RC, Sherk HH, Kollmer C, et al. Cystic lymphangioma in the adult: an unusual axillary mass.Magn Reson Imaging 1989;7:561–563.
16. Curran AJ, Malik N, McShane D, et al. Surgical management of lymphangiomas in adults. J Laryngol Otol 1996;110:586–589.
17. Oakes MJ, Sherman BE. Cystic hygroma in a tactical aviator: a case report. Mil Med 2004;169:985–987.
18. Rossi G, Iannicelli E, Almberger M, et al. Cystic lymphangioma of the upper extremity: US and MRI correlation (2004:11b). Eur Radiol 2005;15:400–402.
19. Gleason TJ, Yuh WT, Tali ET, et al. Traumatic cervical cystic lymphangioma in an adult. Ann Otol Rhinol Laryngol 1993;102:564–566.
20. Kennedy TL, Whitaker M, Pellitteri P, et al. Cystic hygroma/lymphangioma: a rational approach to management. Laryngoscope 2001;111:1929–1937.
21. Nosan DK, Martin DS, Stith JA. Lymphangioma presenting as a delayed posttraumatic expanding neck mass. Am J Otolaryngol 1995;16:186–189.
22. Sherman BE, Kendall K. A unique case of the rapid onset of a large cystic hygroma in the adult.Am J Otolaryngol 2001;22:206–210.
23. Sheth S, Nussbaum AR, Hutchins GM, et al. Cystic hygromas in children: sonographic-pathologic correlation. Radiology 1987;162:821–824.
24. Sermon A, Gruwez JA, Lateur L, et al. The importance of magnetic resonance imaging in the diagnosis and treatment of diffuse lymphangioma. Acta Chir Belg 1999;99:230–235.
25. Mahboubi S, Potsic WP. Computed tomography of cervical cystic hygroma in the neck. Int J Pediatr Otorhinolaryngol 1989;18:47–51.
26. Borecky N, Gudinchet F, Laurini R, et al. Imaging of cervico-thoracic lymphangiomas in children.Pediatr Radiol 1995;25:127–130.
27. Ito K, Murata T, Nakanishi T. Cystic lymphangioma of the spleen: MR findings with pathologic correlation. Abdom Imaging 1995;20:82–84.
28. Boxen I, Zhang ZM, Filler RM. Lymphoscintigraphy for cystic hygroma. J Nucl Med 1990;31:516–518.
29. Yuan Z, Chen L, Luo Q, et al. The role of radionuclide lymphoscintigraphy in extremity lymphedema.Ann Nucl Med 2006;20:341–344.
30. Liu N, Wang C, Sun M. Noncontrast three-dimensional magnetic resonance imaging vs lymphoscintigraphy in the evaluation of lymph circulation disorders: a comparative study. J Vasc Surg2005;41:69–75.
31. Mikhail M, Kennedy R, Cramer B, et al. Sclerosing of recurrent lymphangioma using OK-432. J Pediatr Surg 1995;30:1159–1160.
32. Gutierrez San Roman C, Barrios J, Lluna J, et al. Treatment of cervical lymphangioma using fibrin adhesive. Eur J Pediatr Surg 1993;3:356–358.