Case Report

Sebaceous Gland Carcinoma of the Right Flank

Authors: Julie M. Swick MD, Pearon G. Lang Jr MD

Abstract

Abstract:Extraocular sebaceous gland carcinoma is a rare cutaneous malignancy which sometimes can grow rapidly. There is no proven effective treatment for metastatic disease, but the tumor can be successfully treated by surgery if diagnosed early. We report an 83-year-old gentleman with a rapidly growing sebaceous gland carcinoma of the right flank which was initially misdiagnosed as a vascular malformation. By the time he was referred, he had widespread metastatic disease and was a candidate for palliative radiation only.

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References

References1. Janjua TA, Citardi MJ, Sasaki CT. Sebaceous gland carcinoma: report of a case and review of literature. Am J Otolaryngol 1997;18:51–54.JanjuaTA]]CitardiMJ]]SasakiCTSebaceous gland carcinoma: report of a case and review of literature.Am J Otolaryngol19971851-542. Pricolo VE, Rodil JV, Vezeridis MP. Extraorbital sebaceous carcinoma. Arch Surg 1985;120:853–855.PricoloVE]]RodilJV]]VezeridisMPExtraorbital sebaceous carcinoma.Arch Surg1985120853-8553. Nelson BR, Hamlet KR, Gillard M, et al. Sebaceous carcinoma. J Am Acad Dermatol 1995;33:1–15.NelsonBR]]HamletKR]]GillardM&etal;Sebaceous carcinoma.J Am Acad Dermatol1995331-154. Lan MC, Lan MY, Lin CZ, et al. Sebaceous carcinoma of the eyelid with neck metastasis. Otolaryngol Head Neck Surg 2007;136:670–671.LanMC]]LanMY]]LinCZ&etal;Sebaceous carcinoma of the eyelid with neck metastasis.Otolaryngol Head Neck Surg2007136670-6715. Dowd MB, Kumar RJ, Sharma R, et al. Diagnosis and management of sebaceous carcinoma: an Australian experience. ANZ J Surg 2008;78:158–163.DowdMB]]KumarRJ]]SharmaR&etal;Diagnosis and management of sebaceous carcinoma: an Australian experience.ANZ J Surg200878158-1636. Heyderman E, Graham RM, Chapman DV, et al. Epithelial markers in primary skin cancer: an immunoperoxidase study of the distribution of epithelial membrane antigen (EMA) and carcinoembryonic antigen (CEA) in 65 primary skin carcinomas. Histopathology 1984;8:423–434.HeydermanE]]GrahamRM]]ChapmanDV&etal;Epithelial markers in primary skin cancer: an immunoperoxidase study of the distribution of epithelial membrane antigen (EMA) and carcinoembryonic antigen (CEA) in 65 primary skin carcinomas.Histopathology19848423-4347. Metze D, Bhardwaj R, Amann U, et al. Glycoproteins of the carcinoembryonic antigen (CEA) family are expressed in sweat and sebaceous glands of human fetal and adult skin. J Invest Dermatol 1996;106:64–69.MetzeD]]BhardwajR]]AmannU&etal;Glycoproteins of the carcinoembryonic antigen (CEA) family are expressed in sweat and sebaceous glands of human fetal and adult skin.J Invest Dermatol199610664-698. Husain M, Blumenschein G, Esmaeli B. Treatment and outcomes for metastatic sebaceous cell carcinoma of the eyelid. Int J Dermatol 2008;47:276–279.HusainM]]BlumenscheinG]]EsmaeliBTreatment and outcomes for metastatic sebaceous cell carcinoma of the eyelid.Int J Dermatol200847276-279