Letter to the Editor

Single Metastasis in the Gallbladder Arising from Adenocarcinoma of the Rectum

Authors: Christof Abächerli, MD, Jürg Metzger, MD


To the Editor:

An 83-year-old man was admitted to our hospital for the surgical treatment of a locally advanced adenocarcinoma of the rectum. Initial staging showed strong evidence for mesorectal lymphadenopathy. Neoadjuvant radiochemotherapy achieved a regression of the primary findings. An extended perineal rectum amputation was performed. Coexistent cholecystolithiasis necessitated cholecystectomy during the primary procedure. The postoperative histological analysis showed the stage ypT3 yNp2 (9/10) pM1 G3 (gallbladder). The unusual histologically diagnosed gallbladder metastasis was confirmed by Alcian blue periodic acid-Schiff (AB-PAS) and immunohistochemical coloring of the signet ring cells with pancytokeratin antibodies.

This content is limited to qualifying members.

Existing members, please login first.

If you have an existing account please login now to access this article or view your purchase options.

Purchase only this article ($15)

Create a free account, then purchase this article to download or access it online for 24 hours.

Purchase an SMJ online subscription ($75)

Create a free account, then purchase a subscription to get complete access to all articles for a full year.

Purchase a membership plan (fees vary)

Premium members can access all articles plus recieve many more benefits. View all membership plans and benefit packages.


1.Lawrence SP, Ahnen JD. Clinical manifestations, diagnosis, and staging of colorectal cancer. Update 2004;12.
2.Abrams HL, Spiro R, Goldstein N. Metastases in carcinoma, analysis of 1000 autopsied cases. Cancer 1950;3:74–85.
3.Bragg LE, Thompson JS. Concomitant cholecystectomy for asymptomatic cholelithiasis. Arch Surg 1989;124:460–462.
4.Juhasz ES, Wolff BG, Meagher AP, et al. Incidental cholecystectomy during colorectal surgery. Ann Surg 1994;219:467–472; discussion 472–474.