Case Report
Spontaneous Remission of B‐Cell Chronic Lymphocytic Leukemia Associated With T Lymphocytic Hyperplasia in Bone Marrow
Abstract
&NA; Spontaneous remissions in B‐cell chronic lymphocytic leukemia (B‐CLL) are rare and none of them has been studied with immunophenotyping (by flow cytometry and immunohistochemistry) and genotyping. In this patient, studied after spontaneous remission had occurred, there was a residual T‐lymphocytic hyperplasia in the bone marrow with a normal CD4:CD8 ratio. Absolute CD4 and CD8 counts and CD4:CD8 ratio in the peripheral blood were normal. Flow cytometry revealed no B‐CLL cells in the peripheral blood and less than 2% B‐CLL cells in the bone marrow.This content is limited to qualifying members.
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