Case Report

Synchronous Tumors: Hodgkin Disease Presenting in Mesenteric Lymph Nodes from a Right Hemicolectomy for Colon Carcinoma

Authors: Joanne M. Quilon, MD, Scott Day, MD, James C. Lasker, MD

Abstract

The authors report the case of a 56-year-old male diagnosed with Hodgkin disease involving the mesenteric lymph nodes recovered from a right hemicolectomy for colonic adenocarcinoma. The liver and bone marrow were also involved by Hodgkin disease. Synchronous colonic carcinoma and lymphoma in the same patient is a rare occurrence, and Hodgkin disease involving the mesenteric lymph nodes is uncommon as well.


Key Points


* Synchronous occurrence of colonic carcinoma and lymphoma is a rare phenomenon, with an estimated probability of 2%.


* Mesenteric lymph node involvement by Hodgkin disease is also uncommon (<5%).


* Presence of multiple primary malignant neoplasms in the same patient is an important consideration in the treatment of patients with carcinoma.

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References

1. Canellos G, Lister AT, Sular J, in Rosenberg S, Canellos G (eds): Hodgkin's Disease. The Lymphomas. lst ed. Philadelphia, WB Saunders Company, 1998, pp 305–329.
 
2. Barron BA, Localio SA. A statistical note on the association of colorectal cancer and lymphoma. Am J Epidemiol 1976;104:517–522.
 
3. Aggarwal P, Sharma S, Wali J, et al. Colonic carcinoma after chemotherapy of Hodgkin's disease. J Clin Gastroenterol 1989;11:340–342.
 
4. Kreiker J, Kattan J. Second colon cancer following Hodgkin's disease: a case report. J Med Libanais1996;44:107–108.
 
5. Petros JG, Argy O. Hodgkin's disease in the mesenteric lymph nodes in a patient with colon carcinoma. Mt Sinai J Med 1990;57:368–370.
 
6. Krikorian JG, Portlock CS, Maunch PM. Hodgkin's disease presenting below the diaphragm: a review.J Clin Oncol 1986;4:1551–1562.
 
7. Thomas DB, Huston BM, Lamm KR, et al. Primary Hodgkin's disease of the sigmoid colon: a case report and review of the literature. Arch Pathol Lab Med 1997;121:528–532.
 
8. Zemsky L, Katz H, Edelman M, et al. Hodgkin's disease involving the large bowel. Clin Colorec Cancer 2001;1:185–186.
 
9. Polk HC, Spratt JS, Butcher HR. Frequency of multiple primary malignant neoplasms associated with colorectal carcinoma. Am J Surg 1985;109:71–74.
 
10. Jaworski RC, Dowton B, Grant A, et al. Colorectal carcinoma and lymphoma. Aust N Z J Surg1982;52:37–38.
 
11. Dinshaw KA, Advani SH, Desai PB, et al. An evaluation of intraabdominal involvement in Hodgkin's disease. J Surg Oncol 1978;10:559–566.
 
12. Mir-Madjlessi SH, Vafai M, Khadeni J, et al. Coexisting primary malignant lymphoma and adenocarcinoma of the large intestine in an IgA-deficient boy. Dis Colon Rectum 1984;27:822–824.
 
13. Sugihara S, Yamaguchi A, Mataumura K, et al. Concurrent malignant lymphomas of the jejunum and multiple synchronous colon cancers. Am J Gastroenterol 1983;78:341–345.
 
14. Krikorian JG, Portlock CS, Rosenberg SA, et al. Hodgkin's disease, stages I and II occurring below the diaphragm. Cancer 1979;43:1868–1871.