Original Article

Treatment of Goodpasture's Syndrome With Immunosuppression and Plasmapheresis

Authors: RICHARD A. FINCH MD, EDWIN A. RUTSKY MD, EOLINE McGOWAN MD, CURTIS B. WILSON MD

Abstract

ABSTRACT:A 14-year-old boy with Goodpasture's syndrome induced by anti-glomerular-basement-membrane (GBM) antibody exhibited declining renal function, in association with a progressive increase in the level of serum anti-GBM antibody. Treatment with prednisone, cyclophosphamide, and plasmapheresis was associated with rapid disappearance of the serum anti-GBM antibody and temporary stabilization of renal function.

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References