Case Report

Trovafloxacin-Induced Weakness Due to a Demyelinating Polyneuropathy

Authors: CLINTON K. MURRAY, MD, GLENN W. WORTMANN, MD

Abstract

Fluoroquinolones have been associated with peripheral sensory disorders and weakness, especially in patients with underlying myasthenia gravis or myasthenia-like Eaton-Lambert syndrome. Trovafloxacin is a relatively new quinolone for which these side effects have not been described. We report a case of diffuse weakness due to a demyelinating polyneuropathy that began after initiation of trovafloxacin in a patient without an underlying neurologic disorder.

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