Issue - Southern Medical Association

Article

Bisphosphonate Therapy for Postmenopausal Osteoporosis

ABSTRACT: Bisphosphonates are agents that are potentially useful for treatment of osteoporosis. They are antiresorptive agents, increasing bone mass by decreasing the frequency of osteoclast activation or the depth of osteoclast resorption, or both. Intermittent cyclical therapy with etidronate has been shown to be effective for postmenopausal osteoporosis in two…

Article

Role of Calcium in Preserving the Skeletal Health of Aging Women

ABSTRACT: During the years from adolescence through senescence, the skeleton passes through identifiable phases: consolidation, maturity, menopause, and senescence. Skeletal dynamics and calcium requirements are different during each phase. An adult woman can avoid the skeletal deterioration caused by calcium deficiency if she maintains a minimum daily calcium intake of…

Article

Vitamin D Metabolism and Therapy in Elderly Subjects

ABSTRACT: Serum 25-hydroxyvitamin D declines in elderly subjects. This decrease reflects, in part, a lower vitamin D intake. But changes in serum 25-hydroxyvitamin D are more marked in the northern latitudes of the world because less vitamin D synthesis occurs in the skin as a result of a reduced amount…

Article

Glucocorticoid-Induced Osteoporosis

ABSTRACT: The incidence of osteoporosis in patients receiving long-term glucocorticoid therapy is 30% to 50%. Trabecular bone is lost more rapidly than cortical. The cause of glucocorticoid-induced bone loss is multifactorial. Gastrointestinal absorption of calcium falls and urinary excretion rises, production of gonadal hormones decreases, and bone formation is inhibited…

Article

Estrogen Therapy for Geriatric Osteoporosis: Just One Ball in a Complex Juggling Act

ABSTRACT: The use of estrogens is the single therapy that has been found consistently to prevent bone loss and fractures in postmenopausal women. Traditional osteoporotic risk factors should be used to select women for bone densitometry. The numeric result provided by densitometry, combined with age-based comparisons, is extremely useful in…

Article

Calcitonin Therapy in Osteoporotic Syndromes

Article

Diagnosis of Osteoporosis

Article

Fluorides and Osteoporosis

Article

Mercy Killing

Article

Osteoporosis: The Problem

Article

Perspectives in the Use of Newer Bisphosphonates in the Management of Established Osteoporosis

Article

The Right To Die: Legal and Ethical Considerations