Original Article

Effect of Hepatitis C Virus Infection on the Left Ventricular Systolic and Diastolic Functions

Background: Hepatitis secondary to infection with the hepatitis C virus (HCV) is one of the most common causes of viral hepatitis worldwide. Multiple extrahepatic manifestations of HCV infection have been recognized. Dilated and hypertrophic cardiomyopathy associated with HCV infection have been recently described in the literature; however, the effect of…

Original Article

Effect of Periodontal Treatment on Lipoproteins Levels in Plasma in Patients with Periodontitis

Objectives: Recent epidemiological studies have shown that individuals with periodontitis have a significantly increased risk of developing coronary heart disease. In addition to conventional risk factors, dyslipidemia may be associated with this increased risk. Methods: We measured concentration of lipids in patients with moderate to severe periodontitis before and 3,…

Invited Commentary

Socioeconomic Disparities in Prostate Cancer Mortality

There is a wealth of information available when combining the US census data with state cancer registries. The article by Wan et al in this month’s issue of the Southern Medical Journal studies the effect of using different geographic groupings on the study of prostate cancer mortality in African Americans…

Original Article

Prevalence, Incidence, and Recurrence of Oral Lesions Among HIV-Infected Patients on HAART in Alabama: A Two-Year Longitudinal Study

Objective: Our aim was to quantify prevalence, incidence, and recurrence of oral lesions (OL) among a population in the Southeast. Methods: A retrospective study based on chart review was conducted among patients (n = 744) who were ≥19 years of age and initiated highly active antiretroviral therapy (HAART) between January…

Original Article

Eliminating Disparities in Hypertension Care for Hispanics and Blacks Using a Heart Failure Disease Management Program

Objectives: This study assessed if patients enrolled in a heart failure disease management program (HFDMP) reach the JNC VII target goals for blood pressure (BP) control, eliminate disparities in hypertension control by race/ ethnicity and the impact BP control has on survival. Methods: Patients (N = 898) with an ejection…

Original Article

Additional Therapeutic Effect of Balneotherapy in Low Back Pain

Objectives: Balneotherapy has been widely used for treatment of chronic low back pain recently. However there are only a few clinical controlled trials on balneotherapy. The aim of the present study was to evaluate the effects of balneotherapy in patients with chronic low back pain. Methods: Sixty patients with lumbar…

Original Article

Second-Line Levofloxacin-Based Triple Therapy’s Efficiency for Helicobacter pylori Eradication in Patients With Peptic Ulcer

Objectives: First-line standard eradication efficacy with lansoprazole, amoxicillin and clarithromycin regressed over 10 years. The aim of this study was to evaluate the efficacy and tolerability of a levofloxacin-based regimen in patients with peptic ulcer after failure of the standard first-line H.pylori eradication therapy in a country with a high…

Original Article

Knowledge of Osteoporosis Among Men in the Primary Care Setting

Objectives: Osteoporosis has been often viewed as a disease affecting women; however, men are at risk for osteoporosis, and the mortality after hip fracture in men older than 75 years of age is significantly higher than in women. We aimed to assess knowledge of osteoporosis and its risk factors in…

Original Article

Should All Patients with Pulmonary Hypertension Undergo HIV Serologic Testing?

Objectives: To evaluate the yield of screening patients with pulmonary hypertension (PH) for human immunodeficiency virus (HIV) infection. Methods: We retrospectively reviewed the records of consecutive patients with PH seen at our institution from July 1992 to November 2008. We assessed HIV risk factors and history of HIV. We estimated…

Original Article

Incidence and Impact of False-Positive Urine Pneumococcal Antigen Testing in Hospitalized Patients

Objectives: Immunochromatographic urine pneumococcal antigen testing (ICT) has become a common diagnostic tool for those presenting with possible invasive pneumococcal disease. The incidence and clinical impact of ICT false-positivity on hospitalized patients has not been assessed outside of specific patient subpopulations. ICT performance needs to be assessed in a real-world…

Original Article

Student-Led Rural Health Fairs: Attempting to Improve Medical Education and Access to Health Care

Objectives: Residents of rural communities, especially in the Southeast, have decreased access to health care. Ensuring medical students receive adequate exposure to their issues is complicated by the urban location of most schools. We describe health fairs conducted in rural communities to suggest how having medical students use screening tools…

Original Article

Well-Child Care in Infancy and Emergency Department Use by South Carolina Medicaid Children Birth to 6 Years Old

Objectives: This analysis tests the hypothesis that children enrolled in Medicaid with the recommended early and periodic screening, diagnosis and treatment (EPSDT) visits in the first 24 months utilize fewer emergency department (ED) services birth to 6 years old than children with fewer visits. Methods: Data represent all health encounters…

Original Article

Iron Insufficiency and Hypovitaminosis D in Adolescents with Chronic Fatigue and Orthostatic Intolerance

Objectives: More than 10% of adolescents suffer from severe fatigue and/or orthostatic intolerance. Adult studies show correlations between iron insufficiency and fatigue as well as between hypovitaminosis D and non-specific pain. We sought to determine whether there were correlations between nutritional factors (iron status, and serum vitamin D levels) and…

Invited Commentary

Place in Therapy for Liraglutide and Saxagliptin for Type 2 Diabetes and FDA Liraglutide Warning

The Food and Drug Administration (FDA) issued a reminder through the MedWatch program to providers on June 13, 2011 that highlighted the risk of thyroid carcinoma and acute pancreatitis with the use of liraglutide (Victoza). This was prompted by a letter from Novo Nordisk, the maker of liraglutide, after an…

Review

Tetanus: A Review

Tetanus is a preventable illness occurring worldwide with a high mortality, mostly affecting neonates in developing countries. Effects are toxin mediated and the diagnosis is clinical. Antibiotics, antitoxin, immunoglobulin and wound care are the mainstays of management.

Original Article

Socioeconomic Disparities in Prostate Cancer Mortality and the Impact of Geographic Scale

Objective: To examine socioeconomic disparities in prostate cancer mortality and to assess the scale effect on the results of the disparity analysis. Methods: Using prostate cancer mortality data (N = 14,036) of Texas from 1996 to 2004, this study examines the variations of socioeconomic disparities in prostate cancer mortality across…

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