Editorial

DISEASE AND THE HLA SYSTEM

Editorial

ORAL THERAPY IN DIABETES MELLITUS—AN UPDATE

Editorial

ACKNOWLEDGMENT

Editorial

Hepatic Adenoma A Possible Complication of Oral Contraceptive Therapy

ABSTRACTThree cases of hepatic adenoma occurred in women, two of whom were taking oral contraceptive medication. The clinical and pathologic data from these and previously reported cases are reviewed. The possible causal relationship between the development of hepatic adenomas and the use of oral contraceptives is explored.

Editorial

Impact of Intensive Newborn Care on Neonatal Mortality in a Community Hospital

ABSTRACTDevelopment of a Perinatal Center delivering Level 3 intensive care in a community hospital is described. The inborn neonatal mortality at the hospital in which the Center is located, as well as that of the 13 surrounding counties, has diminished more rapidly than the state neonatal mortality. This has coincided…

Editorial

Myocardial Infarction in Patients Less Than 45 Years Old Acute Course, Angiographic Findings, and Long‐Term Follow‐Up

ABSTRACTThe clinical courses of 57 patients who had an acute myocardial infarction when less than 45 years of age were reviewed to identify descriptors which might be useful in selecting candidates for coronary artery surgery. Follow-up for the subgroup of 45 patients seen initially with acute myocardial infarction was 98%…

Editorial

The Effectiveness of Topical and Oral Tetracycline for Acne*

ABSTRACTA group of 135 college students with acne was evaluated in a 12-week, double-blind study comparing placebo, oral tetracycline 0.5 gm daily, and a new topical tetracycline preparation. The topical tetracycline preparation, containing n-decyl methyl sulfoxide to enhance penetration, produced statistically significant improvement of acne as compared to placebo after…

Editorial

Cancer of the Esophagus Ten‐Year Experience

ABSTRACTA critical analysis of 52 patients with cancer of the esophagus indicates the continuing challenge that this disease entity presents to the surgeon and radiotherapist. Difficulty of cure or palliation is further compounded by the many significant associated medical problems found in certain patient populations, such as that characteristic of…

Editorial

Clinical Usefulness of Radioimmunoassay of Thyrotropin A Review

Editorial

Colposcopic Management of Abnormal Cervical Cytology During Pregnancy*

ABSTRACTA total of 104 pregnant patients with abnormal cervical cells were referred to the Dysplasia Clinic for evaluation and management by colposcopy. Seventy-one pregnant patients presenting with basal cell atypia on cytologic examination had colposcopically directed biopsy revealing 8.45% severe dysplasia and 1.41% carcinoma in situ. Cytologic study in 31…

Editorial

Associated Systemic Factors in Cerebrovascular Ischemia

ABSTRACTSystemic disorders (eg, cardiac, hematologic) are commonly recognized as predisposing and sometimes actual precipitating events in cerebral ischemia. From available studies, the incidence of precipitation is not clear. To determine this, we undertook a comprehensive investigation of all patients with ischemic brain disease for a one-year period. Results reveal that…

Editorial

The Problem of Splenectomy in a Leukemic Patient Population*

AbstractAn attempt has been made in an experimental group of 20 patients, with leukemia or one of the myelo-proliferative disorders, to devise a safe method of splenectomy by timing the operation to coincide with optimal response to chemotherapy, preoperative bowel preparation with antibiotics to minimize infections, and availability of platelet…

Case Report

Hypoventilation After High Unilateral Cervical Chordotomy in a Patient With Preexisting Injury of the Phrenic Nerve

Case Report

Placenta Previa and Preeclampsia Complicating the Management of Renal Transplant Patients

AbstractPresented are three patients who have delivered full-term normal infants after renal transplants from living related donors. One patient had a placenta previa with excessive vaginal hemorrhage. Another patient manifested preeclampsia. Management of these and other complications should be aggressive and thorough with special precautions taken to preserve graft function….

Case Report

Transient Ischemic Attacks Not Produced by Extracranial Vascular Disease A Plea for Complete and Early Angiographic Investigation

AbstractSix patients with classical transient ischemic attacks that were not directly related to extracranial carotid disease are presented. These cases were selected to include a variety of pathologic conditions: one case each of brain tumor, arteriovenous malformation, chronic subdural hematoma, cervical spondylosis, and two cases of giant intracranial aneurysms. These…

Case Report

Palliative Treatment of Carcinoma of the Esophagus*

AbstractIn a ten-year period 139 patients with epidermoid carcinoma of the esophagus were treated by palliative feeding procedures, palliative radiation therapy, radiation therapy for cure, or resection. Analysis of the results of these modes of therapy indicates that long-term palliation is best achieved when resection is the primary method of…

Case Report

Yolk Sac Carcinoma

AbstractYolk sac carcinoma is an uncommon neoplasm which has appeared under a variety of names. It has been reported not only in gonadal sites but also in the mediastinum, pineal body, and sacral areas. The typical histologic appearance of this tumor and the variety of locations are demonstrated by four…

Book Review

Davis‐Christopher Textbook of Surgery

Book Review

Breast Cancer—A Personal History and an Investigative Report

Book Review

Diet and Dermatosis

AbstractDiet and medical history of 1,058 physicians and dentists and their wives were analyzed. Five parameters of refined carbohydrate consumption were found to be significantly (p

Book Review

Small‐Bowel Obstruction A Review of 465 Cases

AbstractA retrospective review of experience with small-bowel obstruction at the University Hospital in Birmingham for a ten-year period (January 1963 through December 1972) revealed 465 episodes of obstruction in 415 patients. The mortality was 4% in obstruction due to adhesions, and 28% in obstruction caused by carcinoma; overall mortality was…

Book Review

Late Pulmonary Function in Survivors of Adult Respiratory Distress Syndrome

ABSTRACTEarly recognition and improvements in treatment have brought an appreciable decline in mortality from the adult respiratory distress syndrome. Physiologic changes during the acute illness include restriction of lung volumes and a defect in gas transfer. Until recently, pulmonary function of long-term survivors has not been discussed. This report concerns…

Book Review

Correction of Extensive Neck Contractures With Local Flaps and Split‐and Full‐Thickness Grafts

ABSTRACTA technic of combined split-thickness and fullthickness skin grafts and local flap closure for extensive deep cicatricial neck contractures is presented. The head and neck are mobilized by excision of limiting tissues. The lateral neck skin is mobilized to be rotated anteriorly as flaps, and a full-thickness skin graft is…

Book Review

Outpatient Chemotherapy of Advanced Breast Cancer in a Community Setting A Five‐Drug Regimen

ABSTRACTForty-two (37 evaluable) unselected women with advanced breast carcinoma were treated with a modified “Cooper regimen” in a community setting. After 12 weeks of induction therapy, the patients were evaluated for response and toxicity. The 74% overall response rate (78% in the evaluable group) compares favorably with that of other…

Book Review

A Surgical Approach in the Treatment of Schistosoma mansoni*

Book Review

Aggressive Treatment of Acute Respiratory Insufficiency*

ABSTRACTTreatment of patients with severe acute respiratory insufficiency included application of end-expiratory pressure to an optimal level, precise cardiovascular monitoring, and adaptation of conventional respirators to provide intermittent mandatory ventilation. Of 90 patients with acute respiratory insufficiency secondary to trauma, sepsis, or complicated surgery, 65% survived. Mortality appeared to be…

Book Review

Vaginal Hysterectomy by an Anterior Colpotomy Technic

ABSTRACTA simple, relatively unknown technic of vaginal hysterectomy using the anterior colpotomy approach is presented. Experience with this procedure at a small Naval hospital is described. Morbidity occurred in 6.6% of the patients. The advantages of this method of vaginal hysterectomy are summarized.

Book Review

Treatment of Chronic Unilateral Frontal Sinusitis by Removal of the Interfrontal Septum*

ABSTRACTExternal surgical treatment of unilateral chronic frontal sinusitis by removal of the interfrontal septum is described. Eleven patients were treated by this method with excellent cosmetic results and only one transient recurrence.

Book Review

Transabdominal Gunshot Wounds of the Hip

ABSTRACTExperience with two cases of transabdominal gunshot wounds of the hip in nonmilitary circumstances indicated delayed recognition of the hip involvement. This delay resulted in compromised end results in both cases. The wartime principles of early recognition and prompt surgical management are recommended for civilian settings.

Book Review

A Diphtheria Outbreak in Dade County, Florida

ABSTRACTDuring a 16-week period in late 1969, 11 cases of diphtheria (three fatal) were reported from Miami, Dade County, Florida. For each of ten previous years, two cases at most had been reported. All patients resided in a predominantly black, low socioeconomic community within the 7-square-mile Model City area. Nine…

Book Review

Malpractice Liability of Physicians to Nonpatients

ABSTRACTSometimes physicians assume responsibilities to third parties when undertaking the care of patients. Physicians have been held liable to third parties, though strangers to the patients, for failing to warn regarding the communicability of contagious diseases. Two suits have been allowed against physicians by third parties who were injured by…

Book Review

The Lower Cervical Spine in Trauma A Study of False‐Negative and False‐Positive Findings

ABSTRACTEvaluation of roentgenographic studies of the lower cervical spine may be complicated by posttraumatic immobility, certain body types, and technical factors which produce equivocal findings. False-positive and false-negative findings are reported, with suggestions for additional views and more diagnostic evaluation.

Clinical Brief

A Modified Solid Ankle Brace for the Treatment of Arthritides*

ABSTRACTA modified solid ankle short leg brace is presented for use in patients with ankle joint and hind foot arthritides. Thirty-five patients were followed up for an average of 21/2 years. Thirty patients had marked relief of pain; three, moderate relief; and two, no relief. Thirty-two patients had improved cosmesis…

Clinical Brief

Statistical Manipulation for Normalization of Data In Vitro Thyroid Function Tests

ABSTRACTInterest in chemical and statistical methods chosen to define “normal” populations for the clinical significance of tests has grown recently. Because few clinical values are distributed in gaussian fashion, recommendations for smoothing of data by transforms have been prepared. In this paper we examine mathematical transformations as they are applied…

Clinical Brief

Duodenal Crypts

ABSTRACTDuring the course of 2,340 barium examinations of the upper gastrointestinal tract, four male patients were found to have multiple small outpouchings on the surface of the duodenal bulb. These findings, designated duodenal crypts, are considered to be asymptomatic and are not to be confused with inflammatory changes. The endoscopic…

Review Article

Anticoagulant‐Induced Necrosis of Skin and Subcutaneous Tissues Report of Two Cases and Review of the English Literature

Review Article

Special Problems for Drugs Used in Children

Article

Leonardo da Vinci Anatomist and Medical Illustrator

Article

Albers‐Schönberg Disease

Current Concepts

Surgical Management of Morbid Obesity Current Considerations in the Use of Extensive Jejunoileal Bypass

Current Concepts

Treatment of Intestinal Parasitic Disease

Case Report

Cystic Hemangioma of the Spleen in a Schizophrenic Patient

Case Report

Peroneal Spastic Flatfoot Syndrome

Case Report

Carpal Tunnel Syndrome Discussion of Operating Technics

Case Report

Wilms' Tumor With Bony Metastases

Case Report

COMMENTS FROM THE READERS

Case Report

“Doing New Orleans”—A Fascinating Experience

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