Editorial

CURRENT STATUS OF LIVER TRANSPLANTATION

Editorial

REOVIRUS‐LIKE AGENTS AS A CAUSE OF HUMAN DIARRHEAL DISEASE

Primary Article

Vacuum Aspiration An Efficient Outpatient Screening Technic for Endometrial Disease

ABSTRACTIn an effort to find a safe, efficient, and inexpensive means of ruling out the existence of a neoplastic process causing abnormal vaginal bleeding from the uterine cavity, 103 patients over 34 years of age had preoperative aspiration (Vabra aspirator) of the endometrial cavity. The tissue obtained at the time…

Primary Article

Cardiac Aspect of Cooley's Anemia

ABSTRACTThe short- and long-term effects of multiple versus regularly spaced blood transfusions on cardiac size, electrocardiographic alterations, heart sounds, murmurs, and carotid pulse were studied in 18 children with Cooley's anemia. These parameters were evaluated before transfusions, one week after multiple blood transfusions (when hemoglobin levels had reached normal), and…

Primary Article

Otolaryngology in the Medical School Curriculum

ABSTRACTWhether the family practitioner will emerge as the primary physician in the area of otolaryngology, with the specialist relegated to either a secondary or tertiary role, remains as yet unsettled. Given the uncertainty of the future place of otolaryngology in general health care, more attention should be placed on teaching…

Primary Article

Detecting Ventricular Arrhythmia After Myocardial Infarction Comparison of Holter Monitoring and Treadmill Exercise

ABSTRACTThe effectiveness of Holter monitoring is compared to modified treadmill exercise for detecting ventricular arrhythmia in 54 patients during the third week after a documented myocardial infarction. Treatment with digoxin and antiarrhythmic agents had been discontinued for 48 hours. Whereas 76% of the patients had no PVCs during treadmill exercise,…

Primary Article

The Psychiatrist's Management of Patients With Undiagnosed Brain Neoplasm

ABSTRACTOf 679 patients with brain neoplasms admitted to either a medical school center or a community hospital during a nine-year period, 24 had been examined by a psychiatrist before definitive diagnosis of brain neoplasm. These 24 cases were studied to evaluate the role of the psychiatrist in the management of…

Primary Article

Irradiation Failures in Cancer of the Larynx

ABSTRACTA series of 116 faryngeal carcinomas treated definitively with irradiation over a 91/2-year period is presented. By preliminary follow-up, there have been 20 recurrences, for an initial treatment failure rate of 17%. Of the 20 patients with recurrence, 16 had salvage surgical procedures. Four of the 16 surgical wounds (25%)…

Primary Article

Hypopituitarism A Complication of Diabetes

ABSTRACTHypopituitarism is a rarely reported accompaniment of diabetes mellitus.1,2 Autopsy studies suggest, however, that pituitary lesions are ten times more common in diabetics than in nondiabetics.3,4 Three cases of diabetes with hypopituitarism are reported. We believe that clinically important hypopituitarism may occur more commonly than is suspected in diabetes and…

Primary Article

Fell Tube Insertion After Orthograde Dilatation of Malignant Esophageal Obstruction Palliation and Morbidity

ABSTRACTTwenty-eight patients with malignant esophageal obstruction had palliative treatment using the Fell endoesophageal tube. The usual plan for these patients, irradiation followed by resection, was not followed because of the presence of tracheoesophageal fistula, celiac or hepatic metastases, or marked debilitation which precluded major operation. Palliation was obtained in ten…

Primary Article

Acute Postinfectious Crural Myalgia in Children

ABSTRACTAn outbreak of acute crural myalgia in children is reported. The severe calf pain followed an influenza-like episode, with subsequent complete recovery. Laboratory studies in most cases showed elevated creatine phosphokinase and SGOT values, with a low peripheral white blood cell count. Electromyographic studies were normal. Results of one muscle…

Book Review

Recent Advances in Plastic Surgery

Book Review

Hematology, Physiologic, Pathophysiologic and Clinical Principles

Book Review

Perinatal Medicine

Book Review

Textbook of Paediatric Nutrition

Primary Article

Medicolegal Implications of the Incompetent, Errant, and “Sick” Physician Changing Times

ABSTRACTA great deal of publicity has been given recently to the problems and consequences of incompetent and errant physicians. There has been great clamor on this subject from many sources—the medical profession, the legal community, the legislatures, the judiciary, and the public. All of these interested parties have undertaken studies…

Primary Article

Studies of Serum Testosterone and Its Reduction Products

ABSTRACTLevels of serum testosterone (T) and its metabolites dihydrotestosterone (D) and androstanediol (A) measured by a competitive protein binding method were as follows, respectively: in adult males (mean ± 1 SD), 435 ± 114, 41 ± 11, 43 ± 12 ng/100 ml; in adult females, 30 ± 14, 18 ±…

Primary Article

The Use of the Carbon Dioxide Laser in Plastic Surgery

ABSTRACTFor centuries, surgical technics have included sharp metal instruments for incisions and dissections together with time-consuming clamping and tying of vessels with associated blood loss. The CO2 laser presents the first major change in these basic technics. Our brief experience with the Sharplan 791 indicates consistently marked reduced blood loss,…

Primary Article

Hematuria and Sickle Cell Disorders

ABSTRACTTo examine the relationship between gross hematuria and sickle cell disorders, all patients admitted to Grady Memorial Hospital with the diagnosis of a sickle cell disorder during a 14-month period were reviewed. Of 115 such patients, 65% had sickle cell disease and 35% had sickle cell trait. None of the…

Primary Article

Primary Carcinoma of the Trachea Report of Two Cases

ABSTRACTPrimary carcinoma of the trachea is not common. Of 23 cases diagnosed as “carcinoma of the trachea” at our institution since 1949, 21 actually represented secondary involvement from carcinoma of the larynx, lung, or esophagus. The two cases of primary carcinoma of the trachea are presented. Discussed are the relation…

Primary Article

Predictors of the Duration of Infectious Mononucleosis

ABSTRACTThe clinical course of infectious mononucleosis was monitored in 122 patients to determine predictors of duration of illness. Gastrointestinal symptoms and palatal petechiae were associated with a prolonged recovery period. Multiple regression analysis of quantitative data identified the number of days from onset of symptoms to diagnosis as the only…

Primary Article

Endobronchial Metastases

ABSTRACTSeventeen cases of endobronchial metastases are reviewed. Of these, six had the primary lesion in the breast. Treatment was by resection, radiation, or systemic therapy. Breast cancer patients with long disease-free intervals had the longest survival after bronchial metastases, and those with the most aggressive carcinomas and sarcomas had shorter…

Primary Article

Minoxidil‐Induced Hypertrichosis Treatment With Calcium Thioglycolate Depilatory

ABSTRACTMinoxidil is a new, effective, investigational antihypertensive drug. A serious, cosmetic side effect in women is hypertrichosis. Five female patients with this complication had successful removal of the excessive hair with a calcium thioglycolate depilatory agent.

Primary Article

Unsterile Intermittent Catheterization for Meningomyelocele

ABSTRACTTwenty-five children with meningomyelocele have been managed by clean unsterile intermittent catheterization (UIC). There were 17 satisfactory results, three total failures, and three partial failures under this regimen. Experience, problems, and causes of failure are discussed. UIC offers a definitive form of management for some types of neurogenic bladder.

Primary Article

Myotonic Muscular Dystrophy in Pregnancy

ABSTRACTMyotonic muscular dystrophy is an autosomal dominant disease inherited with variable penetrance. With pregnancy, the myotonia and muscle weakness may increase. There is also an increased incidence of abortion, prematurity, fetal death, labor dysfunction, and postpartum hemorrhage. A description of two pregnant patients and a review of the literature illustrate…

Article

Anorexia Nervosa A Combined Therapeutic Approach

ABSTRACTTen female patients with a diagnosis of anorexia nervosa were treated with a combination of behavior modification and psychotherapy and, when appropriate, psychotropic medication. All patients had favorable weight gain and improvement in adjustment during hospitalization. Later crises for each patient thus far have not significantly affected their weight. Three…

Article

Atopic Dermatitis The Concept of Flare Factors

ABSTRACTA flare factor is a biologic or environmental factor which induces exacerbation of atopic dermatitis. Xerosis, sweating, scratchy clothes, allergy, infection, scratching, allergic contact dermatitis, anxiety, and coexisting disease are potential flare factors. Different patients have different flare factors, and individual patients may have different flare factors at different times….

Article

The Effect of Serum Oncotic Pressure on Serum Cholesterol Levels A Study in “Normal” and Nephrotic Subjects

ABSTRACTClinical data in nephrotic and nonnephrotic subjects were examined to help delineate the mechanism of hypercholesterolemia in nephrotic syndrome. Analyses of the relationship between total serum cholesterol and serum albumin levels and between total serum cholesterol and calculated serum oncotic pressure in 500 nonnephrotic individuals revealed strong positive correlations (r…

Article

Injuries From Sea Urchins

ABSTRACTInjuries from sea urchins result from penetration of the calcareous spines into the skin. Local pain of several days' duration is the most common symptom, but systemic reaction from toxins found in certain species can occur. There is no uniformly accepted successful treatment other than cleansing the wound. Attempts to…

Article

Benign Tumors of the Esophagus Experience With 20 Cases

ABSTRACTBenign tumors of the esophagus are rare and require an alert suspicion for early diagnosis. These tumors may not cause symptoms before attaining large size, yet they may prove fatal when small. Because of the possibility of malignancy and their tendency to obstruct, benign tumors of the esophagus should be…

Article

Arthroscopy Its Role in Treating Nontraumatic and Traumatic Lesions of the Knee

ABSTRACTArthroscopy of the knee is a useful adjunct in the diagnosis and treatment of intra-articular disease. We reviewed 178 patients who had arthroscopy at Duke from November 1972 to May 1975. Anesthesia was either general or local with a block of the intrapatellar fat pad and the intrapatellar branch of…

Review Article

Digitalis Glycosides—Recent Advances in Clinical Pharmacology and Treatment

Current Concepts

Avoiding a Pitfall in Resuscitation The Painless Cervical Fracture

ABSTRACTFor the physician treating an injured patient, it is important to recognize fracture of the cervical spine without neck pain. Films of the cervical spine in patients with head or facial trauma, or patients who are unconscious, inebriated, or have multiple injuries, should be routine and are best obtained by…

Current Concepts

Chloramphenicol Toxicity

Article

Eponym Edwards Crisp The Splenic Anatomist

Case Report

Pathogenesis of Kerley's B Lines on the Chest Roentgenogram

Case Report

Dermatofibrosarcoma Protuberans—Case Reports and Review of Literature

Case Report

Massive Cavernous Hemangioma of the Liver

Case Report

Clinical and Echocardiographic Manifestations of a Thrombosed Bjork‐Shiley Aortic Value

Case Report

Gamma Heavy Chain Disease—Presenting as Pancytopenia and Splenomegaly

Case Report

Agenesis of the Gallbladder—An Inherited Defect?

Case Report

Perforating Granuloma Annulare

Case Report

Pulmonary Dirofilariasis Another Coin Lesion

Case Report

Intracranial Meningioma Containing Metastatic Foci

Case Report

The Columnar‐Cell-Lined (Barrett's) Esophagus A Premalignant Condition?

Case Report

Malignant Lymphoma of the Nasopharynx in Waldenström's Macroglobulinemia Report of a Case With Severe Epistaxis

Case Report

Platypnea and Hypoxemia in Laennec's Cirrhosis of the Liver

Case Report

Hodgkin's Disease Presenting in Epitrochlear Lymph Nodes

Letter to the Editor

LETTERS TO THE EDITOR

Letters to the Editor are welcomed. They may report new clinical or laboratory observations and new developments in medical care or may contain comments on recent contents of the Journal. They will be published, if found suitable, as space permits. Like other material submitted for publication, Letters must be typewritten…

Letter to the Editor

Mohs' Chemosurgery

Case Report

Acute Hypertension After Abrupt Withdrawal of Antipsychotic Medication

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