Editorial

PENICILLIN‐RESISTANT GONOCOCCI RESULT OF PLASMID PROMISCUITY

Editorial

ROLLIN A. DANIEL, JR., MD

Editorial

GENERAL ANNOUNCEMENTS

Commentary

THROMBOELASTOGRAPHIC DISTINCTION OF MALIGNANT AND BENIGN BREAST MASSES

Primary Article

Thromboelastographic Distinction of Malignant From Benign Breast Masses A Preliminary Report

ABSTRACTThromboelastography is a newly applied tool for the detection of carcinoma. By comparing the thromboelastograph (TEG) of fresh whole blood (native) to that of blood to which celite has been added (celite activated), enhanced clotting is manifested which allows identification of individuals harboring carcinoma. Twenty women, obtained in a random…

Case Report

Pebble Ingestion An Unusual Form of Geophagia

Primary Article

Use of Salt Bridge in Rhythm Analysis

ABSTRACTFilling a catheter with electrolyte solution converts it to a conductor and allows the safe recording of an electrogram from near or within the right atrium. This technic is very useful in localizing the internal position of a cardiac catheter and particularly in rhythm analysis. Four cases are presented to…

Primary Article

Association of Breast Cancer With Myeloproliferative Disorders

ABSTRACTThree cases of myeloproliferative disorders in patients with breast cancer are described. The first patient developed acute myeloblastic leukemia 26 years after her initial breast cancer; the second patient developed chronic myelogenous leukemia three years after the diagnosis of breast cancer; the third patient had polycythemia vera for nine years…

Primary Article

A Pediatric Residency Program Revisited

ABSTRACTThere have been few assessments of residency programs by graduates; therefore, to investigate a practical means of evaluating programs we asked former trainees to relate aspects of their training to present professional needs. Former residents in the Duke pediatric program from 1960 to 1972 were asked to evaluate various aspects…

Primary Article

Clinical Considerations of the Ratio of Myocardial Oxygen Demand to Available Supply

ABSTRACTMyocardial oxygen demand is the relationship between the inherent needs of the heart and the available oxygenated blood reaching the myocardial tissue. The system is controlled by two different, yet not wholly uncomplementary, mechanisms. The first, coronary blood flow, appears to be regulated primarily by tissue oxygen tension. The second,…

Primary Article

Evaluation of Posterior Fossa Lesions by Computer Assisted Tomography (CAT)

ABSTRACTValuable neuroradiologic information can be obtained with routine examination of the posterior fossa by computer assisted tomography (CAT). The diagnosis can be difficult in the posterior fossa due to the relatively small size of the compartment and its proximities to large bony masses and air in the mastoid cells. However,…

Primary Article

Bleeding, Clotting, and Functional Disability Following Beall Prosthetic Mitral Valve Replacement

ABSTRACTThe incidence of fatal and nonfatal thromboemboli and bleeding episodes was compared in 53 patients who received sodium warfarin and in 17 successive patients who received no sodium warfarin after Beall mitral valve replacement. Actuarial curves showed that by 12 months postoperatively patients not receiving sodium warfarin had a greater…

Primary Article

A Controlled Clinical Trial of Two Local Agents in Postepisiotomy Pain and Discomfort

ABSTRACTPostepisiotomy pain can be an annoying complication for physicians and nurses to manage after an otherwise uneventful delivery. A controlled prospective study was conducted in 100 parturients to test the relative efficacy of two agents. Of 50 patients given a mucoadhesive foam containing a local anesthetic plus a corticosteroid, 82%…

Primary Article

Treatment of Patellar Fractures by Partial Patellectomy

ABSTRACTResults of treating 238 transversé, longitudinal, and osteochondral fractures of the patella are reviewed. Of these, 89 patients had partial patellectomy and extensor mechanism reconstruction. After an average follow-up of four years, functional results have been excellent; there have been no late patellectomies and traumatic arthritis has not developed. Total…

Primary Article

The Outpatient Treatment of Refractory Hypertension With Minoxidil

ABSTRACTMinoxidil is a potent orally administered vasodilator under investigation for use in severe hypertension. Fifteen patients with moderate to severe hypertension refractory to conventional antihypertensive drugs were treated with minoxidil on an outpatient basis. Propranolol and furosemide were administered concomitantly to control reflex tachycardia and fluid retention. Good blood pressure…

Primary Article

Nonunion of Fractures of the Proximal Humerus A Method of Treatment Using a Modified Moe Plate

ABSTRACTTreatment of nonunion of fractures of the proximal or middle third of the humerus by use of a modified Moe plate is described. We have found this treatment to produce more favorable results than other methods using either internal or external immobilization. Simple modification of an existing mechanically sound device…

Primary Article

Scar Carcinoma Prognosis and Treatment

ABSTRACTA 30-year experience with 31 cases of squamous cell carcinoma arising in scars is reviewed. Mean age of the patients was 58 years. Average time from injury to diagnosis was 23 years. The male to female ratio was 4:1. Tumors were well differentiated in 23 cases and poorly differentiated in…

Primary Article

Endocarditis Treated With Clindamycin Relapse and Liver Dysfunction

ABSTRACTClindamycin was used to treat six patients with endocarditis because of allergy to penicillin in five, and an unfavorable clinical response to methicillin in one. Only one patient had an uneventful cure with clindamycin. Two had hepatotoxicity which resolved rapidly after clindamycin was stopped. Two patients, one of whom had…

Primary Article

Leukemia and Prostatism

ABSTRACTBenign prostatic hyperplasia associated with chronic lymphocytic leukemia is relatively rare. Needle biopsy is indicated to determine the possible benefits of radiation therapy as compared to surgery. Although overall mortality is high, transurethral resection (TUR) is well tolerated and may be undertaken without undue concern. An additional case is reported.

Primary Article

Investigating the Contacts and Suspected Contacts of Tuberculous Patients in New Orleans

ABSTRACTThe New Orleans Health Department still investigates the contacts and suspected contacts of patients with tuberculosis, although it has stopped some tuberculosis control programs as unproductive. To determine whether contact investigation is worthwhile, in 1974 we sampled 1,110 men, women, infants, and children who had proved (391) or suspected (719)…

Primary Article

Pseudocholinesterase Deficiency An Additional Preoperative Consideration in Outpatient Diagnostic Procedures

ABSTRACTBecause pseudocholinesterase deficiency is an unusual anesthetic complication which requires specialized equipment and postanesthetic management and nursing care for successful treatment, it takes on added significance when it occurs in the ambulatory surgical patient. It emphasizes the fact that while operative procedures performed in the ambulatory surgical setting may be…

Primary Article

Testing for the Tay‐Sachs Gene in the Atlanta Jewish Population

ABSTRACTIn May 1975, three mass screening clinics for the asymptomatic Tay-Sachs carrier were held in Atlanta, Georgia. Ninety percent of the 2,330 adults screened were of Ashkenazi Jewish ancestry. One hundred seventy-six people were identified as possible carriers, 145 returned for retesting, and 74 were diagnosed as carriers. The Tay-Sachs…

Primary Article

Visual Field Status in the Management of Chronic Angle‐Closure Glaucoma

ABSTRACTA retrospective analysis of the case histories of 40 patients with chronic angle-closure glaucoma yielded 31 eyes without visual field loss and 26 eyes with field loss. Peripheral iridectomy was highly successful in cases without field loss. Trabeculectomy was significantly more successful (93%) than iridectomy (64%) in treating cases with…

Review Article

Spontaneous Pneumothorax in the Neonate

Current Concepts

Antineoplastic Chemotherapy

Current Concepts

The Cephalosporin Antibiotics in Pediatric Practice

ABSTRACTThe efficacy of the cephalosporins against grampositive cocci and some of the gram-negative bacilli together with their relative safety make this family of antibiotics potentially useful in treating pediatric infections, particularly in instances of penicillin hypersensitivity. Newer cephalosporins have broadened the antimicrobial spectral range and may offset some of the…

Article

Eponym Helen Brooke Taussig

Case Report

Addison's Disease Secondary to North American Blastomycosis

Case Report

Simultaneous Infection of the Central Nervous System With Cryptococcus neoformans and Mycobacterium intracellulare

Case Report

Spontaneous Subcutaneous Emphysema of the Neck and Mediastinum

Case Report

Pseudomonas Endocarditis Cure With Carbenicillin and Polymyxin B

Letter to the Editor

Somatostatin Lowering of LH Levels in a Postmenopausal Woman

Case Report

Nonpuerperal Inversion of the Uterus by Endometrial Stromal Sarcoma of the Uterine Fundus

Case Report

Osteogenic Sarcoma in a Patient With Aplastic Anemia

Case Report

New Behavioral Data Concerning the Autoerythrocyte Sensitization Syndrome

Case Report

Ventricular Tachycardia in a Patient With the “Chinese Restaurant Syndrome”

Case Report

Cholangiographic Findings in Agenesis of the Gallbladder

Case Report

Peutz‐Jeghers Polyposis With Metastasizing Duodenal Carcinoma

Case Report

Henoch‐Schönlein Purpura of the Colon An Unusual Gastrointestinal Manifestation

Case Report

Paranasal Aspergilloma Caused by an Albino Variant of Aspergillus fumigatus

Case Report

Endometriosis of the Umbilicus

Article

Big D For A Rousing Time!

The stars at night are big and bright, deep in the heart of Texas. The sage in bloom is like perfume, deep in the heart of Texas.

Original Article

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