We describe two unusual cases of platypnea. The first patient had chronic obstructive pulmonary disease, but platypnea did not respond to chronic obstructive pulmonary disease therapy. He was found to have multiple pulmonary emboli, and symptoms rapidly improved on anticoagulation therapy. The second patient had Parkinson disease and developed severe…
Expired CME Credit Submission and Evaluation Form – Platypnea-orthodeoxia
Published health benefits of regular light-to-moderate alcohol consumption include lower myocardial infarction rates, reduced heart failure rates, reduced risk of ischemic stroke, lower risk for dementia, decreased risk of diabetes and reduced risk of osteoporosis. Numerous complimentary biochemical changes have been identified that explain the beneficial effects of moderate alcohol…
Amebic liver abscess is the most common extraintestinal manifestation of infection with Entamoeba histolytica, and it is associated with significant morbidity and mortality. In this article the most recent available information is reviewed relating to epidemiology, pathogenesis, presentation, diagnosis, and treatment. We reviewed thousands of cases of amebic liver abscess…
Pseudallescheria boydii is a ubiquitously occurring fungus. While rarely causing opportunistic infection in humans, it is the most common cause of fungal pneumonia in cases of near drowning, and is associated with high mortality. P boydii typically causes cutaneous mycetomas but may invade the lungs or brain. P boydii infections…
Dengue fever is a major public health problem worldwide. Dengue hemorrhagic fever, a much rarer form of the disease, occurs when a person previously infected with dengue is re-infected with a different viral serotype. In recent years the infection rates of dengue and both clinical syndromes have increased along the…
Cryptococcal skin lesions are found in 10 to 15% of patients with disseminated cryptococcosis. Primary skin inoculation by Cryptococcus neoformans is rare but has been reported. We report the first known case of primary cutaneous cryptococcosis in a lung transplant recipient. Our patient, a 57-year-old man, underwent left single-lung transplantation…
Topotecan HCl is an antitumor drug exhibiting topoisomerase I-inhibitory activity. Topotecan is used in the treatment of metastatic carcinoma of the ovary and as second-line treatment of small-cell lung cancer. Reported dose-limiting adverse reactions to topotecan are primarily hematologic in nature. To date, only one other case of lung toxicity…
Most cases of Pseudomonas pyarthrosis affecting the sternoclavicular joint have been reported in immunosuppressed intravenous drug users. We report a case of Pseudomonas pyarthrosis in a man who was otherwise immunocompetent, except for his age. A 66-year-old white man presented to the clinic with a 1-month history of right-sided shoulder…
Objectives: Sexually transmitted diseases (STDs) remain at high levels in the South compared with the rest of the nation. Physician diagnosis levels and screening behaviors fall among the elements about which more knowledge is needed to address these high levels. This article assesses Southern physicians’ STD diagnosis histories and screening…
Objectives: Cystic hygroma is associated with chromosomal abnormalities and a low chance of survival. The purpose of this study was to examine the relationship between cystic hygroma and various clinical and demographic factors. Methods: Cystic hygroma cases delivered in Hawaii from 1986 to 1999 were obtained from a population-based birth…
We present a series of three patients who suffered penetrating thoracic injury, and in whom thoracic packing was used as a life-saving procedure. Survival among these patients paralleled the severity and extent of the original injuries. Restriction of cardiac filling and lung expansion are potential deterrents from using this technique;…
Objectives: Accurate reptile envenomation mortality data for the United States is unavailable. Using data from the National Vital Statistics System (NVSS), deaths from 1979 through 1998 were analyzed. Methods: Records of deaths from reptile envenomation were selected using matches to code E905.0 of the International Classification of Diseases, Ninth Revision….
Objectives: Regional deficits in cerebral blood flow have been reported in a few studies of fibromyalgia; however, there is no information on the effects of treatment and clinical recovery on these abnormalities. We evaluated the effects of amitriptyline treatment and consequent clinical recovery on cerebral blood flow changes in fibromyalgia….
Blastoschizomyces capitatus is an emerging fungal pathogen. It has been well characterized as a cause of local and disseminated disease in immunocompromised hosts, especially in the setting of neutropenia. We describe a case of B capitatus pneumonia in an otherwise healthy man and review the clinical presentation, microbiologic characteristics, and…
The case is reported of an elderly patient with known previous exposure to fire ant stings, and who presented with hand-foot syndrome (HFS) in the setting of multiple fire ant stings to the lower extremities. Both hands and both feet were red, swollen, and mildly tender. Treatment was with fluocinonide…
Tuberculosis (TB) has been described in association with malignancies including Hodgkin disease (HD). We report three cases of simultaneous occurrence of TB and HD. In two of these cases clinical symptoms improved after TB treatment was instituted and before HD was diagnosed. Fever recurrence in one case and persistence of…
“To encourage right choices, we must be willing to confront the dangers young people face—even when they’re difficult to talk about. Each year, about 3 million teenagers contract sexually transmitted diseases that can harm them, or kill them, or prevent them from ever becoming parents. In my budget, I propose…
Cystic hygroma is a congenital abnormality linked to lymphatic malformations. Should lymphatic vessels fail to connect and drain, they may result in a large, multilocal cyst. Cystic hygromas are most commonly found on the neck, but can also be found in other areas. With advanced diagnostic technologies, clinicians are better…
To the Editor: Pruritus ani (PA) is an unpleasant sensation of itching and an urge to scratch the skin around the anal orifice. It is very common and a socially embarrassing condition which is often poorly managed. PA is classified as idiopathic when there is an absence of any apparent…
To the Editor: The existence of ventricular shunt malfunctions among patients with neurocysticercosis, mentioned by Psarros et al in the October issue of the Southern Medical Journal, has been previously reported. 1 This is well known to be related to the inflammatory reaction within the subarachnoid space in patients with…
Objectives: Allen County, KY, is a rural county with a population of approximately 18,000. The county has a tobacco crop and is in a state in which tobacco interests are influential. The tobacco control program at the public health department developed a goal to reduce environmental tobacco smoke by restricting…
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