ABSTRACT: A 17-year-old girl had linear and dermatomal lichenoid chronic graft-versushost disease (GVHD) 18 months after receiving an allogeneic bone marrow transplantation for aplastic anemia. The cutaneous GVHD lesions appeared on previously normal skin.
ABSTRACT: Although left ventricular filling tends to occur in late diastole in the elderly, the clinical significance of this change is unclear. To determine the prevalence of diastolic filling delay and its relationship to congestive heart failure (CHF) in the elderly, we studied 114 community-living elderly volunteers (median age 75,…
ABSTRACT: Although patients with factitious disorders typically seek the “patient” role through illness portrayals, some instead portray themselves falsely as “victims.” We discuss the cases of four women who claimed to have been victims of rape; the allegations ultimately were disproved. Factitious rape may be prompted by a search for…
ABSTRACT: Here we describe a case of unexplained CD4+ T-lymphocyte depletion and cryptococcal meningitis in a patient without evidence of human immunodeficiency virus (HIV) infection. This newly recognized syndrome has been named idiopathic CD4+ lymphopenia (ICL). When HIV infection is suspected in a patient with an opportunistic infection, a CD4+…
ABSTRACT: Hydroxyurea is a cytotoxic agent that is being increasingly used for a number of malignant and nonmalignant systemic diseases. This agent is particularly well tolerated, with dose-related myelosuppression being the primary side effect. We describe a patient who had patchy interstitial infiltrates with cavitation 2 months after the start…
ABSTRACT: I describe the case of a 25-year-old man who, after a scuba dive, had ocular barotrauma caused by mask squeeze. As in most cases, the condition occurred because the patient failed to exhale into the mask during descent to equalize the pressure within the mask. Although alarming in appearance,…
ABSTRACT: In this study, 1,027 healthy men over age 40 were screened for prostate cancer with digital rectal examinations (DRE) and prostate-specific antigen (PSA) levels. Findings were abnormal in 189 (18%). PSA levels alone were abnormal (> 4.0 ng/mL) in 111 men (12%), 60 men (8%) had abnormal DRE and…
ABSTRACT: Lithium therapy for bipolar illness is well accepted, despite some difficulties with its use. The administration of anticonvulsants has increased over the past 20 years. This paper outlines advantages and problems associated with anticonvulsant therapy for mood disorders.
ABSTRACT: Malignant pleural effusion (MPE) causes significant morbidity in cancer patients. Management is often challenging because of the recurrent nature of MPE and the inconsistent response rates of various treatments. In patients whose underlying malignancy is unresponsive to systemic chemotherapy or radiation, MPE is usually managed by tube thoracostomy with…
ABSTRACT: Medical records of 118 newborn infants with Down's syndrome were reviewed to document the types of congenital heart disease (CHD) in those having echocardiography. Of 102 infants having echocardiography, 49 (48%) had heart defects; 47 of these had trisomy 21 and 2 had unbalanced translocation karyotypes. Of the 53…
ABSTRACT: Patients with noncardiac chest pain frequently have some evidence of gastroesophageal reflux. Yet there are few formal studies on the treatment of what appears to be reflux-related chest pain. The purpose of this study was to evaluate the effectiveness of intensive antireflux therapy in patients with noncardiac chest pain…
ABSTRACT: Progress toward state and national Year 2000 Objectives for reduction in smoking prevalence and smoking-attributable mortality were analyzed for Kentucky, a major tobacco-growing state. Phone survey data indicated a 0.6% annual decrease in smoking prevalence from 1985 to 1992. This decrease is not sufficient to achieve state or national…
ABSTRACT: Recent advances have made available to the clinician multiple serologic tests for the diagnosis and evaluation of acute and chronic viral hepatitis. While the multiplicity of tests available can be confusing, selective use of these serologic tests tailored to the clinical situation can be of great value in identifying…
ABSTRACT: Relapsing polychondritis (RP) is an autoimmune disorder with chondritis as a prominent clinical feature. This disease has been found to coexist in some patients with systemic lupus erythematosus (SLE) or vice versa. We report a patient with clinical criteria fulfilling the diagnosis of RP. She had elevated levels of…
ABSTRACT: Reports of blastomycosis in individuals infected with the human immunodeficiency virus (HIV) are increasing. We report on 3 patients co-infected with blastomycosis and HIV (to add to the previously reported 21), and review important clinical aspects and outcomes in all cases. The percentage of patients co-infected with blastomycosis and…
ABSTRACT: The objective of this study was to determine the ability of a software program used in a primary care physician's office to predict the need for alternate living arrangement in a cohort of community-dwelling elderly. An analysis was conducted involving 124 consecutive patients between February 10, 1990, and December…
ABSTRACT: This retrospective study examined the clinical course of 18 prepubertal boys (aged 6 to 12) who had dual diagnoses of attention deficit hyperactivity disorder and conduct disorder and who received clonidine on an inpatient basis after failed trials of conventional drug therapy, consisting predominantly of psychostimulants. The effects of…
ABSTRACT: Venous thrombosis is a frequent complication in patients with paroxysmal nocturnal hemoglobinuria (PNH). However, arterial thrombosis is rare, and cerebral arterial thrombosis has been reported only in postmortem studies. We discuss the case of a PNH patient in whom both clinical and neuroimaging findings were compatible with cerebral arterial…
ABSTRACT: We describe a 22-year-old woman who developed fever, shaking chills, and leukocytosis after insertion of a terconazole (80 mg) vaginal suppository for mild vaginal candidiasis. The patient became afebrile and asymptomatic 24 hours after hospital admission without antibiotic therapy. More experience with terconazole is needed before it can be…
ABSTRACT: We describe the cases of two asymptomatic patients who had carpet beetle larval parts in routine cervical Pap smears. The diagnosis was made by finding pathognomonic hastisetae in the smears. The evidence suggests that contamination occurred at or around the time of sampling.
ABSTRACT: We discuss the cases of four immigrant workers in whom lead intoxication developed via inhalation while they were cutting steel beams removed from a dismantled bridge. They all had toxic lead levels with symptoms and received chelation therapy; the therapy was followed by a decrease in blood lead levels….
ABSTRACT: We reviewed the clinical courses of children ≤16 years of age with hereditary hemolytic anemias who were admitted to the University of Mississippi Medical Center for aplastic crisis. Constitutional signs, gastrointestinal complaints, and headache were the most frequent findings. Statistically significant decreases in hemoglobin levels, hematocrit, and reticulocyte counts,…
Membership grants access to journals, courses and a slew of premium benefits.
Please consider supporting us by choosing an option below:
View Membership Options Make A Tax-Deductable Donation
No Thanks, take me to the site and don't show me this again.