Editorial

HYPOXEMIA A PERIL OF SLEEP

Primary Article

Rocky Mountain Spotted Fever in the United States Use of Age-Specific Incidence to Determine Public Health Policy for a Vector-Borne Disease

ABSTRACTThe increasing national and regional incidence of Rocky Mountain spotted fever (RMSF) during the past two decades led us to look at nationally collected epidemiologic data on reported cases of RMSF for 1975 through 1978, paying special attention to age-specific incidence in the states where the disease is most common….

Primary Article

Reliability of Histopathologic Diagnosis of Cervical Intraepithelial Neoplasia

ABSTRACTA study was designed to measure the inter-pathologist consistency of histopathologic diagnosis of cervical intraepithelial neoplasia (CIN) among four pathologists. Intra-pathologist reliability over time was also determined. Between-pathologist comparisons resulted in agreement only 50% of the time; however, 81% of pairs were within one CIN grade of each other. Seventy-one…

Primary Article

“Early” Carcinoma of the Breast Evaluation of Regional Therapy and Features Influencing Prognosis

ABSTRACTBetween 1944 and 1969, 192 women with carcinoma of the breast were treated at The University of Texas System Cancer Center M. D. Anderson Hospital and Tumor Institute by standard radical mastectomy for small outer quadrant lesions and pathologically negative axillary lymph nodes. Twenty percent of these patients with “localized…

Primary Article

Immunodeficiency in Children With Severe Craniofacial Anomalies

ABSTRACTIn immunologic studies of 20 children with severe facial birth defects, all were evaluated for quantity of T and B cells, immunoglobulins, and the third component of complement. Only 18 patients could be evaluated for blastogenesis and 16 for chemotaxis. Forty percent of the children had a decreased quantity of…

Primary Article

Causes of Refusal to Walk in Childhood

ABSTRACTRefusal to walk is a common complaint in childhood. Its etiology was investigated by reviewing the charts of children who were admitted to the hospital with this problem in a one-year period. Bacterial infections produced 22 of the 55 episodes and were more likely to be associated with fever than…

Primary Article

Pulmonary Function Changes After Acute Inhalation of Chlorine Gas

ABSTRACTFour young healthy adults were studied physiologically after accidental inhalation of chlorine gas. All patients were symptomatic with cough, tightness in the chest, and shortness of breath. All had restrictive ventilatory defect with impaired diffusing capacity. There was evidence of some obstruction in small airways. There was inconsistent evidence of…

Primary Article

Ventricular Cardiac Arrhythmias During Anesthesia Feasibility of Preoperative Recognition

ABSTRACTWe investigated the occurrence of anesthetic ventricular cardiac arrhythmia (CA) in 104 systemically healthy consecutive patients undergoing general anesthesia, to evaluate the possibility of recognizing preoperatively those patients prone to CA. In 19 (18%) patients, control strips taken before anesthesia showed CA. During anesthesia CA developed in 34 (33%), including…

Primary Article

Radiation Therapy for Renal Transplant Rejection Reactions

ABSTRACTForty-four renal transplant patients were given radiation therapy for severe rejection phenomena. The 29 patients who had only one course of irradiation had a 52.3% successful function rate. Fifteen patients received from two to four courses of irradiation with an ultimate 60% rate of sustained function. Fifty patients who received…

Primary Article

Declining Mortality From Hypertension and Stroke

ABSTRACTRecorded mortality from hypertension and stroke has decreased dramatically in most countries during the last 50 to 75 years. The reported reduction in mortality may be due to changes in diagnostic fashions or coding procedures. However, the magnitude and consistency of the decline suggests the occurrence of a true decrease….

Review Article

Sleep Apnea Syndromes

ABSTRACTThe sleep apnea syndromes have been recognized clinically in the United States only within the past ten years. The true extent of the problem is not known, but it seems certain that these syndromes are much more common than was generally assumed five years ago. Every clinician should be aware…

Current Concepts

The Double Contrast Barium Enema Why Bother?

ABSTRACTDespite a wealth of publications extolling the virtues of the double contrast barium enema (DCBE), it is clear that change is only gradual and that in many institutions the single contrast, full column barium enema (BE) is still the routine method of colonic investigation.1 Much of this may be due…

Article

Genetic Misconceptions

ABSTRACTClinical genetics is becoming an increasingly important part of general medical practice. Much of what most physicians know about this relatively new field has been learned informally. Unfortunately, this has resulted in some erroneous information being accepted as empirical fact. We have compiled this list of “genetic misconceptions” to prevent…

Article

The Cricket and the Marionette

Our Medical Heritage

Intravenous Therapy From Humble Beginnings Through 150 Years

Case Report

Obstructive Sleep Apnea After Lateral Medullary Syndrome

Case Report

Subdural Empyema An Unusual Complication of Meningococcal Meningitis

Case Report

Control of Intrahepatic Bleeding by Superselective Embolization of the Middle Hepatic Artery

Case Report

Precordial Honk in Association With Tricuspid Valve Prolapse

Breif Report

Sepsis Associated With Nonperforated Appendicitis

Breif Report

Overwhelming Group B Streptococcal Sepsis After Splenectomy in an Adult

Breif Report

Pulmonary Hypertension After Primary Closure of a Gastroschisis

Breif Report

Meningitis Caused by Haemophilus influenzae Type e, Biotype 4

Breif Report

Monocytic Leukemia in a 2-Year-Old Child

Breif Report

Acute Myelogenous Leukemia After Successful Treatment of Small Cell Carcinoma of the Lung

Breif Report

Isoniazid-Induced Exfoliative Dermatitis

Breif Report

Acute Gouty Arthritis Presenting as Polyarticular Disease

Letter to the Editor

Oops!

Letter to the Editor

Amphotericin B Toxicity

Subject Index

SUBJECT INDEX

Author Index

AUTHOR INDEX

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