SMJ articles in the category "metformin"

Original Article

Propensity Score Matching to Determine the Impact of Metformin on All-Cause Mortality in Older Veterans with Diabetes Mellitus

Objectives: To determine whether metformin is associated with reduced all-cause mortality in older adults with diabetes mellitus as compared with insulin or sulfonylureas, and to evaluate whether the metformin cumulative exposure followed a dose-response relation. Methods: Retrospective cohort study with propensity score matching inveterans 65 years old and older with…

Posted in: diabetes mellitus 34 metformin 5 veterans 7

Original Article

Retrospective Chart Review of Children With Type 2 Diabetes Mellitus Evaluating the Efficacy of Metformin vs. Insulin vs. Combination Insulin/Metformin

Objectives: Type 2 diabetes mellitus is a growing problem in pediatrics and there is no consensus on the best treatment. We conducted this chart review on newly diagnosed pediatric patients with type 2 diabetes mellitus to compare the effect of treatment regimen on body mass index (BMI) and hemoglobin A1c…

Posted in: hemoglobin A1c 5 insulin 8 metformin 5 Obesity 70 pediatrics 33 type 2 diabetes mellitus 13

Review

Recent Diabetes Issues Affecting the Primary Care Clinician

Diabetes accounts for millions of office visits each year to primary care offices in the United States. Successful care of the patient with type 2 diabetes requires not only focus on glucose management but also on comorbidities such as hypertension, dyslipidemia and obesity which are closely linked to microvascular and…

Posted in: Cardiovascular Disease 27 liraglutide 2 metformin 5 primary care 64 rosiglitazone 2 saxagliptin 2 Statins 8 type 2 diabetes mellitus 13

Case Report

Metformin-Induced Vitamin B12 Deficiency Presenting as a Peripheral Neuropathy

Chronic metformin use results in vitamin B12 deficiency in 30% of patients. Exhaustion of vitamin B12 stores usually occurs after twelve to fifteen years of absolute vitamin B12 deficiency. Metformin has been available in the United States for approximately fifteen years. Vitamin B12 deficiency, which may present without anemia and…

Posted in: deficiency 3 Diabetes 23 metformin 5 neuropathy 3

Review Article

Achieving Glycemic Control in Type 2 Diabetes: A Practical Guide for Clinicians on Oral Hypoglycemics

Type 2 diabetes mellitus has reached epidemic proportions in the United States. Cardiovascular morbidity and mortality are particularly high in this patient population. Improved glucose control, especially early in the course of diabetes, can slow or prevent complications, preserve β-cell function, and improve long-term outcomes. Within the last decade, new…

Posted in: metformin 5 sulfonylureas 2 thiazolidinediones 2 type 2 diabetes mellitus 13
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