Original Article

Decreased Maternal Weight Gain in Pregnancy Is Seen with Buprenorphine Medication-Assisted Treatment

Objectives: Medication-assisted treatment (MAT) is associated with low maternal weight gain, and low maternal weight gain is associated with infant mortality. Many MAT patients also are smokers. This study investigates buprenorphine administration during pregnancy as a possible independent risk factor for low maternal weight gain. To our knowledge, this is…

Posted in: buprenorphine 8 pregnancy 48 weight gain 2

Original Article

Sexually Transmitted Infection Screening and Positivity in Pregnant Women Living in Areas with High Social Vulnerability Indices

Objectives: Pregnant women living in rural areas of the United States are not equitably served by healthcare systems and may be disproportionately affected by sexually transmitted infections (STIs). We examined the impact of location of pregnancy care on STI screening and positivity in a statewide health system. Methods: Pregnant women…

Posted in: chlamydia 3 gonorrhea 2 pregnancy 48 social vulnerability 2 trichomoniasis 2

Review Article

Restless Leg Syndrome and Pregnancy

Objective: The purpose of this assessment of the literature was to evaluate the etiology, incidence, risk factors, diagnosis, management, and recurrent risk in a subsequent pregnancy of restless leg syndrome (RLS) in pregnancy. Methods: Electronic databases (PubMed, Embase, and Web of Science) were searched from January 1980–February 2024. The only…

Posted in: Diagnosis 17 etiology 3 management 10 pregnancy 48 restless leg syndrome 2

Original Article

CME Article: Rise in Neonatal Abstinence Syndrome Rate Is Associated with Increase in Buprenorphine Prescription Numbers

Objectives: Southern Appalachia is a region of the United States that is disproportionately affected by the opioid epidemic and by increasing rates of neonatal abstinence syndrome (NAS). NAS rates increased approximately 400% between 1999 and 2012. Buprenorphine prescriptions written to treat opioid use disorder also increased dramatically. The present study…

Posted in: buprenorphine 8 medication-assisted therapy 3 neonatal abstinence syndrome 7 pregnancy 48

Original Article

Effect of Integrase Strand Transfer Inhibitor Use on Time to HIV Viral Suppression before Delivery

Objectives: We sought to determine whether pregnant individuals with human immunodeficiency virus (HIV) prescribed integrase strand transfer inhibitor (INSTI) antiretrovirals (ARVs) achieve viral suppression faster than individuals taking non-INSTI regimens and to determine whether there were differences in viral suppression at delivery among INSTI ARVs. Methods: This is a retrospective…

Posted in: human immunodeficiency virus 23 perinatal 2 pregnancy 48

Original Article

Predictors of Skin, Hair, and Nail Supplement Use: Analysis of National Health and Nutrition Examination Survey (NHANES) Cross-Sectional Data

Objectives: Approximately half of US adults use dietary supplements, often for dermatologic purposes. When survey respondents in a nationally representative population were asked the reasons for their use of a specific supplement, 87% chose “for healthy skin, hair, and nails.” Despite widespread use, supplements have potential risks and lack regulatory…

Posted in: demographics 2 predictors 3 pregnancy 48

Review Article

Comprehensive Review of Hypertensive Disorders Related to Pregnancy

Hypertensive disorder of pregnancy is a common complication during pregnancy that affects approximately 10% of pregnancies and is responsible for nearly 14% of maternal deaths worldwide. It affects the mother and the fetus simultaneously, sometimes putting the health of the mother and the fetus at odds with each other. It…

Posted in: eclampsia 3 Hypertension 39 preeclampsia 4 pregnancy 48

Original Article

Cesarean Delivery Management of Stillbirth: In-Depth Analysis of 75 Cases in a Rural State

Objective: To analyze the characteristics surrounding women who underwent cesarean delivery for stillbirth management in the rural, southern US state of Arkansas. Methods: This was a planned secondary analysis of a retrospective descriptive study evaluating mode of delivery following the stillbirth of singleton pregnancies without anomalies or aneuploidy delivered in…

Posted in: cesarean delivery 3 management 10 mode of delivery 2 pregnancy 48 stillbirth 4

Review Article

Evidence for Prophylactic Transfusion during Pregnancy for Women with Sickle Cell Disease

The objective of this study was to examine prior studies on maternal and neonatal outcomes with prophylactic compared with emergent blood transfusion in pregnant women with sickle cell disease. A review of the literature was performed. Twenty-one articles were identified and included in the analysis. A generalized linear mixed-effects model…

Posted in: maternal mortality 2 pregnancy 48 sickle cell 4

Original Article

Enhancing Patient–Provider Breastfeeding Conversations: Breastfeeding Intention and Prenatal Breastfeeding Self-Efficacy among a Sample of Pregnant Women

Objectives: The purpose of this study was to investigate and identify which sociodemographic factors may be associated with breastfeeding intention and breastfeeding self-efficacy among pregnant women. Methods: Pregnant women at a medical center in Alabama completed a cross-sectional survey. The Prenatal Rating of Efficacy in Preparation to Breastfeed Scale (PREP…

Posted in: pregnancy 48

Original Article

Pregnancy Risk Screening and Counseling for Women Veterans: Piloting the One Key Question in the Veterans Healthcare Administration

Objectives: Women veterans have a high prevalence of comorbidities that increase the risk of adverse pregnancy outcomes. Screening for pregnancy desires in primary care provider (PCP) visits offers an opportunity to optimize preconception health. This pilot quality improvement initiative sought to assess Veterans Healthcare Administration provider preferences on One Key…

Posted in: pregnancy 48 women veterans 2

Original Article

Changes in For-Profit Medication-Assisted Therapy Clinics in an Appalachian City

Objectives: This study is a follow-up to previous research regarding buprenorphine medication-assisted therapy (MAT) in Johnson City, Tennessee. For-profit MAT clinics were surveyed to determine changes in tapering practice patterns and insurance coverage during the last 3 years. Methods: Johnson City for-profit MAT clinics; also called office based opioid treatment…

Posted in: buprenorphine 8 medication-assisted therapy 3 pregnancy 48

Original Article

Prevention of Neonatal Abstinence Syndrome in an Outpatient Prenatal Buprenorphine Tapering Program

Objectives: Many addicted pregnant patients receiving buprenorphine medication-assisted therapy (MAT) wish to discontinue this medication while pregnant. This study was undertaken to determine whether outpatient detoxification from buprenorphine during pregnancy is safe and effective when confirmed with postdetoxification urine drug screens (UDSs). Methods: This case series reports the maternal and…

Posted in: medication-assisted therapy 3 neonatal abstinence syndrome 7 pregnancy 48

Original Article

Opioid Use Among HIV-Positive Pregnant Women and the Risk for Maternal–Fetal Complications

Objective: To assess patient- and hospital-level characteristics associated with opioid use in human immunodeficiency virus (HIV)–positive pregnant women and fetal health outcomes. Methods: Using the 2002–2014 Nationwide Inpatient Sample database, we analyzed discharge records to describe the rates of opioid use among HIV-positive pregnant women. Logistic regression was used to…

Posted in: HIV 30 opioid use 2 pregnancy 48

Original Article

A Population-Based Study of Factors Associated with Postpartum Contraceptive Use by Birth Interval Length

Objective: The purpose of this study was to evaluate factors associated with postpartum contraceptive use among women with short and moderate-to-long birth intervals using population-based data from the Pregnancy Risk Assessment and Monitoring System. Methods: Because only Mississippi and Tennessee include a question about birth interval length on their Pregnancy…

Posted in: contraception 14 postpartum 6 pregnancy 48

Original Article

High Prevalence of Buprenorphine in Prenatal Drug Screens in an Appalachian City

Objectives: To define the magnitude of buprenorphine presence in the urine drug screens of pregnant women and to assess the presence of illicit buprenorphine use versus the presence of prescribed buprenorphine use.Methods: Initial prenatal drug screen results for all pregnant patients in our practice for a 1-year period were analyzed…

Posted in: buprenorphine 8 pregnancy 48

Original Article

Increasing Prevalence of Chronic Hepatitis C Virus Infection in a Southern Academic Obstetrical Clinic

Objectives: The opioid epidemic has resulted in rising rates of hepatitis C virus (HCV) infection in women of childbearing age. With this changing epidemiology in mind, the Infectious Diseases Society of America/American Association for the Study of Liver Diseases guidelines were updated in 2018 to recommend screening all pregnant women…

Posted in: hepatitis C virus 5 obstetrics 6 opioid use disorder 6 pregnancy 48

Original Article

Association of the Length of the Third Stage of Labor and Blood Loss Following Vaginal Delivery

Objectives: The length of the third stage of labor is correlated with blood loss following a vaginal delivery. We aimed to accurately measure blood loss following a vaginal delivery and examine the relation between blood loss and length of the third stage of labor. Methods: This was a prospective observational…

Posted in: blood loss 2 hemorrhage 7 pregnancy 48

Review Article

Chronic Kidney Disease in Pregnancy

With the increasing prevalence of chronic kidney disease (CKD) worldwide, the number of pregnant women with various degrees of renal dysfunction is expected to increase. There is a bidirectional relation between CKD and pregnancy in which renal dysfunction negatively affects pregnancy outcomes, and the pregnancy can have a deleterious impact…

Posted in: Acute kidney injury 5 chronic kidney disease 13 Hypertension 39 pregnancy 48

Original Article

Management of Intrauterine Contraception in Early Pregnancy

Objectives: Women with rare intrauterine contraception (IUC) failures are advised to have their IUC removed because of the risk of poor obstetric outcomes with a retained IUC. Specifics regarding IUC removal in early pregnancy including techniques for removal, rates of success, and immediate pregnancy outcomes following removal are not well…

Posted in: pregnancy 48
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