Original Article

Lack of Association Between Chemokine Receptor 5 (CCR5) δ32 Mutation and Pathogenesis of Asthma in Iranian Patients

Background: Chemokines and their receptors are clinically important mediators, as the chemokine receptors are expressed on almost all immune cells. They play pivotal roles in pathogenesis of almost all clinical situations including asthma. Correspondingly, MIP-1α (CCL3), MIP-1β (CCL4), and RANTES (CCL5) are among the important chemokines involved in the pathogenesis…