Original Article

Regional Differences in Hospitalizations among Patients Admitted with Chronic Obstructive Pulmonary Disease

Objective: Extreme temperatures negatively impact pulmonary function. This study explored whether the variability in ambient temperatures across disparate geographic regions in the United States was associated with differences in hospital outcomes for patients admitted with chronic obstructive pulmonary disease (COPD). Methods: Using the 2016–2019 National Inpatient Sample database, we compared…

Posted in: big data 2 COPD 10 hospitalization 13 outcomes 19

Original Article

Efficacy of Prophylactic Policy–Driven Tranexamic Acid Administration during Cesarean Delivery in a Rural Healthcare Setting

Objectives: Postpartum hemorrhage (PPH) is a major contributor to maternal mortality worldwide and is a leading cause of pregnancy-related mortality in the United States. The American College of Obstetricians and Gynecologists, the Royal College of Obstetricians and Gynecologists, and the World Health Organization advocate for the early use of tranexamic…

Posted in: cesarean delivery 3 efficacy 2 outcomes 19 postpartum hemorrhage 2

Original Article

Effects of Preoperative COVID-19 Status on Emergent or Urgent Colectomy Outcomes

Objectives: Severe acute respiratory syndrome coronavirus 2 has been described as eliciting a powerful immune response. The association of coronavirus disease 2019 (COVID-19) infection with diseases requiring emergent or urgent colectomies may exacerbate the risk of surgical complications. We investigated the effect of preoperative COVID-19 infection on the clinical outcomes…

Posted in: colectomy 3 COVID-19 55 outcomes 19 SARS-CoV-2 7

Original Article

Comparisons between White and Black Patients Hospitalized with Postliver Transplant Complications/Failure

Objectives: The impact of race on patients presenting to North American hospitals with postliver transplant complications/failure (PLTCF) has not been studied fully. We compared in-hospital mortality and resource utilization outcomes between White and Black patients hospitalized with PLTCF. Methods: This was a retrospective cohort study that evaluated the years 2016…

Posted in: big data 2 hospitalizations 2 liver transplant 3 outcomes 19 race 15

Original Article

Association of Obesity on Outcomes of Hospitalized Patients with Cerebral Palsy

In hospitalized adult patients with cerebral palsy, obesity did not lead to significantly higher resource utilization.

Posted in: cerebral palsy 6 hospitalizations 2 Obesity 70 outcomes 19

Original Article

Does Point-of-Care Ultrasound Affect Outcomes in Pediatric Patients with Skin and Soft Tissue Infections?

Objective: There is increasing evidence for the use of point-of-care ultrasound (POCUS) in pediatric patients with skin and soft tissue infections (SSTI), but there is a lack of sufficient data on its impact on SSTI outcomes. The objective of this study was to determine whether POCUS use is associated with…

Posted in: outcomes 19 Pediatric 11 skin and soft tissue infection 2 ultrasound 13

Original Article

Impact of Obesity in Hospitalized Patients with Heart Failure: A Nationwide Cohort Study

Objectives: Obesity and cardiovascular disease remain significant burdens on the overall provision of health care in the United States. Obesity has been shown to be a direct risk factor for heart failure (HF). We conducted a nationwide cohort study to assess the short-term impact of obesity in hospitalized patients with…

Posted in: heart failure 21 mortality 38 Obesity 70 outcomes 19 readmission 6

Original Article

Hospital Readmission Rates Following AMI: Potential Interventions to Improve Efficiency

Objectives: Quality of care utilization measures for patients admitted to the hospital with an acute myocardial infarction (AMI) include length of stay (LOS) and 30-day readmission rates. Our aim was to test whether efforts resulting in reduced LOS in patients diagnosed as having AMI would result in a higher risk…

Posted in: acute myocardial infarction 7 outcomes 19 readmissions 4 utilization 2

Original Article

Association Between Energy Prices and US Hospital Patient Outcomes

Objective: To evaluate associations between changing energy prices and US hospital patient outcomes. Methods: Generalized estimating equations were used to analyze relationships between changes in energy prices and subsequent changes in hospital patient outcomes measures for the years 2008 through 2014. Patient outcomes measures included 30-day acute myocardial infarction, heart…

Posted in: health economics 2 health services research 10 outcomes 19 sustainability 2

Original Article

Video-Assisted Thoracoscopic versus Open Lobectomy: Costs and Outcomes

Objectives: Video-assisted thoracoscopic (VATS) lobectomy is considered a promising surgical therapy for the diagnosis and treatment of non–small-cell lung carcinoma. The issue of whether VATS is superior to open thoracotomy remains controversial, however. We sought to determine whether the use of VATS lobectomy for diagnosing and treating non–small-cell lung carcinoma…

Posted in: lobectomy 4 minimally invasive surgery 3 outcomes 19 thoracotomy 4

Original Article

Intravenous Thrombolysis Attenuates Neurologic Deterioration After Ischemic Stroke

Introduction: Although intravenous tissue plasminogen activator (IV tPA) is associated with neurologic deterioration (ND) caused by hemorrhage, whether it attenuates deterioration as a result of other etiologies including progressive stroke remains unexplored. The objective of this study was to determine whether IV tPA is associated with a reduced risk of…

Posted in: outcomes 19 thrombolysis 7

Review Article

Utility of the Shock Index and Other Risk-Scoring Tools in Patients with Gastrointestinal Bleeding

Patients with upper gastrointestinal (GI) bleeding frequently require hospitalization and have a mortality rate that ranges from 6% to 14%. These patients need rapid clinical assessment to determine the urgency of endoscopy and the need for endoscopic treatment. Riskscoring tools, such as the Rockall score and the Glasgow-Blatchford score, are…

Posted in: gastrointestinal bleeding 8 outcomes 19 shock index 2 transfusions 2

Original Article

Impact of Evidence-Based Guidelines on Outcomes of Hospitalized Patients With Clostridium difficile Infection

Objectives: Clostridium difficile infection (CDI) is the most common healthcare-associated infection in the United States. Clinical practice guidelines for the treatment of CDI were updated in 2010 by the Society for Healthcare Epidemiology of America and the Infectious Diseases Society of America. An institutional guideline for the classification and management…

Posted in: Clostridium difficile 10 Guidelines 10 hospital medicine 15 outcomes 19

Original Article

Outcomes of Lobar and Sublobar Resections for Non–Small-Cell Lung Cancer: A Single-Center Experience

Objectives: Lung cancer is the leading cause of cancer-related mortality in the United States. Kentucky has the highest age-adjusted lung cancer rate and has one of the highest death rates from lung cancer in the country. Lobectomy is considered the standard therapy for non–small-cell lung cancer (NSCLC), whereas sublobar resection…

Posted in: lobectomy 4 neoadjuvant therapy 3 nonsmall cell lung cancer 2 outcomes 19

Original Article

Modern Management of Thoracic Empyema

Objectives: Historically, surgical management of empyema was performed predominantly via open thoracotomy; however, during the past decade the use of video-assisted thoracoscopic surgery (VATS) as an alternative has increased. This study retrospectively compared the outcomes and management of patients with empyema at the University of Kentucky Medical Center who had…

Posted in: empyema 3 outcomes 19 surgery 23 thoracotomy 4 video-assisted thoracoscopic surgery 3

Original Article

Pediatric Osteosarcoma: A Single Institution’s Experience

Objectives: The aim of the study was to evaluate outcomes with an examination of individual predictors influencing survival at a single institution. Methods: This was a retrospective review of the 28 pediatric osteosarcoma patients diagnosed and studied from 2000 through 2012. Twenty-eight patient charts and imaging studies were reviewed for…

Posted in: Mississippi 7 outcomes 19 pediatrics 33

Original Article

Prevalence, Treatment, and Outcomes of Renal Conditions in Pediatric Sickle Cell Disease

Objectives: Vaso-occlusive events in pediatric sickle cell disease (SCD) may cause various renal complications and lead to renal failure. We describe the renal conditions that develop among young patients with SCD and the factors associated with the prevalence of these nephropathies. Materials and Methods: Medicaid medical and pharmacy claims for…

Posted in: outcomes 19 pediatrics 33 sickle cell disease 28

Original Article

Protected Carotid Artery Stenting in Patients at High Risk for Carotid Endarterectomy

Objectives: To compare the 30-day, six-month, and one-year outcomes of carotid artery stenting (CAS) and carotid endarterectomy (CEA) in male veterans, and to identify any predictors of adverse outcomes. CAS has been shown to be non-inferior to CEA in patients at high-risk for CEA. The outcome of CAS compared to…

Posted in: outcomes 19 predictors 3

Original Article

Colchicine Exposures: The Texas Experience

Objectives: Colchicine is a relatively uncommon toxin, but is known to precipitate severe multiorgan failure in overdose. Little is known about exposure patterns and outcomes in cases of colchicine ingestion. Our goal was to add to toxicologic knowledge through a database review and descriptive study of colchicine exposures. Methods: Texas…

Posted in: colchicine 2 outcomes 19 toxicity 10
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