SMJ articles in the category "vitamin D"

Original Article

Outcomes of Clostridioides difficile in Patients with Vitamin D Deficiency: A Propensity-Matched National Inpatient Sample Analysis

Objectives: We aimed to determine in-hospital outcomes, length of hospital stay, and resource utilization in a contemporary cohort of Clostridioides difficile infection (CDI) and vitamin D deficiency (VDD). Methods: The National Inpatient Sample database for 2016 and 2017 was used for data analysis using International Classification of Diseases, Tenth Revision,…

Posted in: morbidity 5 mortality 38 vitamin D 17

Original Article

Weight-Bearing Physical Activity Influences the Effect of Vitamin D on Bone Turnover Markers in Patients with Intellectual Disability

Objectives: Individuals with intellectual disabilities (IDs) are at increased risk for low bone mass and fragility fractures, and those who are nonambulatory may be at even higher risk. Patients with IDs often are vitamin D deficient, but there is little information concerning how vitamin D treatment of patients with IDs…

Posted in: fracture 7 osteomalacia 3 Osteoporosis 29 vitamin D 17

Original Article

Bone Mineral Density and Vitamin D Levels in HIV Treatment-Naïve African American Individuals Randomized to Receive HIV Drug Regimens

Objectives: Treatment of human immunodeficiency virus (HIV)–infected patients with tenofovir disoproxil fumarate is associated with a decrease in bone mineral density (BMD). Treatment with efavirenz is associated with vitamin D deficiency. We compared the effects of efavirenz, emtricitabine, and tenofovir disoproxil fumarate (EFV/FTC/TDF) with the effects of raltegravir, darunavir, and…

Posted in: antiretroviral therapy 7 bone mineral density 6 vitamin D 17

Original Article

Vitamin D Deficiency in Pediatric Patients with Cystic Fibrosis: Associated Risk Factors in the Northern United States

Objectives: Cystic fibrosis (CF) is associated with vitamin D deficiency, which can lead to adverse effects including recurrent pulmonary infections and osteoporosis. We longitudinally investigated calcifediol or 25-hydroxyvitamin D (25(OH)D) levels for our pediatric patients with CF based on the time of year as well as vitamin D supplementation dosing…

Posted in: cystic fibrosis 6 vitamin D 17

Original Article

Occurrence of Vitamin D Deficiency in Pediatric Patients at High Risk in West Virginia

Objectives: Vitamin D deficiency is prevalent and is increasingly associated with the development of medical conditions both related and unrelated to bone metabolism. The purpose of this study was to examine vitamin D deficiency in patients of a pediatrics subspecialty practice. Methods: The study consisted of a retrospective chart review…

Posted in: chronic illness 2 chronic kidney disease 13 cystic fibrosis 6 Obesity 70 vitamin D 17

Original Article

Can a Model Predictive of Vitamin D Status Be Developed From Common Laboratory Tests and Demographic Parameters?

Objectives: Vitamin D deficiency is highly prevalent and has been linked to increased morbidity and mortality. There has been an increase in testing for vitamin D with a concomitant increase in costs. While individual factors are significantly linked to vitamin D status, prior studies have not yielded a model predictive…

Posted in: vitamin D 17

Review

Protean Manifestations of Vitamin D Deficiency, Part 1: The Epidemic of Deficiency

Abstract: Just when vitamin deficiencies were thought to be a “thing of the past” a new vitamin deficiency-that of vitamin D has developed over the past 20 years. Vitamin D works like a hormone being produced primarily in one organ (the kidney) before circulating through the bloodstream to multiple organs…

Posted in: Autoimmune disease 2 Cancer 19 Cardiovascular Disease 27 Diabetes 23 vitamin D 17

Review

Vitamin D Deficiency in Patients with Congestive Heart Failure: Mechanisms, Manifestations, and Management

Recent research suggests that vitamin D may play a role in cardiovascular (CV) health. Although its exact role is still debated and is a matter of controversy, vitamin D deficiency has been linked to increased prevalence of CV risk factors and events. Factors that predispose persons with congestive heart failure…

Posted in: Congestive Heart Failure 11 hypocalcemia 5 secondary hyperparathyroidism 3 vitamin D 17

Review

Clinical Significance of Vitamin D Deficiency in Primary Hyperparathyroidism, and Safety of Vitamin D Therapy

Vitamin D deficiency occurs more frequently in patients with primary hyperparathyroidism (PHPT) compared with the general population, and is usually associated with an aggravated form of the disease. Current guidelines recommend measurement of serum levels of 25-hydroxy vitamin D (25-OHD) in all patients with PHPT, and their repletion if the…

Posted in: hypercalcemia 10 primary hyperparathyroidism 3 vitamin D 17

Expired CME Article

Algorithm for the Management of Osteoporosis

Osteoporosis is a common skeletal disease that weakens bones and increases the risk of fractures. It affects about one half of women over the age of 60, and one third of older men. With appropriate care, osteoporosis can be prevented; and when present, it can be easily diagnosed and managed….

Posted in: FRAX 2 osteopenia 5 Osteoporosis 29 vitamin D 17

Original Article

Effects of Vitamin D Supplementation on Blood Pressure

Objective: Inconsistent findings from epidemiological studies have continued the controversy over the role of oral vitamin D supplementation in reducing blood pressure in normotensive or hypertensive populations. Methods: We performed a literature search up to December 2009, with no restrictions. Only double-blind randomized controlled trials (RCTs) of oral vitamin D…

Posted in: blood pressure 10 meta-analysis 5 vitamin D 17

Case Report

Resolution of Statin-Induced Myalgias by Correcting Vitamin D Deficiency

Correction of hyperlipidemia with statins is often limited by the side-effect of statin-induced myalgias. Vitamin D deficiency is also associated with myalgias that resolve with correction of the vitamin D deficiency. Myalgias associated with statin therapy may also resolve with correction of vitamin D deficiency. This case report presents a…

Posted in: Hyperlipidemia 4 myalgias 2 myositis 2 Statins 8 vitamin D 17

Case Report

Refractory Diffuse Bony Pain 20 Years After Jejunoileal Bypass

Osteomalacia can be a late but unrecognized complication following jejunoileal bypass. We describe a 53-year-old man who underwent jejunoileal bypass for morbid obesity twenty years earlier who suffered from progressive diffuse bony pain refractory to nonsteroidal anti-inflammatory drugs. He was initially diagnosed with a malignancy with bone metastasis. However, pertinent…

Posted in: hypocalcemia 5 hypophosphatemia 2 osteomalacia 3 vitamin D 17

Case Report

The Lack of Vitamin D Toxicity with Megadose of Daily Ergocalciferol (D2) Therapy: A Case Report and Literature Review

Abstract:The maximum daily dose of vitamin D currently recommended is 2000 IU. Ergocalciferol (D2) 50,000 IU orally weekly for 8–12 weeks is often used to treat vitamin D deficient patients (25(OH) vitamin D <20 ng/mL). The lack of vitamin D toxicity after massive doses of ergocalciferol has yet to be…

Posted in: vitamin D 17

Case Report

Vitamin D as Adjunctive Therapy in Refractory Pulmonary Tuberculosis&colon; A Case Report

Abstract:Vitamin D regulates calcium homeostasis in the body and may play a major role in regulating immune responses to tuberculosis (TB). Pilot studies suggest that vitamin D supplementation may improve outcomes in pulmonary TB (PTB), but clinical evidence using vitamin D in TB treatment is limited. We present a case…

Posted in: immunity 2 Treatment 22 tuberculosis 13 vitamin D 17

Original Article

Prevalence of Vitamin D Deficiency and Insufficiency in Northeast Tennessee

Background: Vitamin D deficiency is increasingly being recognized as a highly prevalent and undertreated problem. This study was conducted to determine the prevalence of vitamin D deficiency/insufficiency in hospitalized adults in northeast Tennessee. Methods: A prospective cohort study was conducted on 99 inpatients admitted to an internal medicine teaching service…

Posted in: 25-hydroxyvitamin D 2 deficiency 3 Prevention 18 vitamin D 17

Review Article

Vitamin D: Important for Prevention of Osteoporosis, Cardiovascular Heart Disease, Type 1 Diabetes, Autoimmune Diseases, and Some Cancers

Vitamin D is very important for overall health and well-being. A major source of vitamin D comes from exposure to sunlight. Measurement of 25-hydroxyvitamin D in the blood and not 1,25-dihydroxyvitamin D is used to determine vitamin D status. A blood level of 25-hydroxyvitamin D of at least 20 ng/mL…

Posted in: vitamin D 17
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