Multidisciplinary Clinical Case Study

An Underappreciated and Prolonged Drug Interaction Leads to Ineffective Anticoagulation

A poorly understood significant drug–drug interaction compounded by ineffective communication among providers at times of care transition most likely contributed to multiple thromboembolic events in an 81-year-old patient. Increased awareness of drug interactions with direct oral anticoagulants (DOACs), as well as improved communication among inpatient and outpatient providers at the…

Posted in: direct oral anticoagulants 2 drug-drug interactions 2 transition of care 4

Review Article

Role of Direct Oral Anticoagulants in the Management of Anticoagulation

For decades, vitamin K antagonists (VKAs) have been the oral treatment of choice for many thromboembolic conditions. The limitations of VKAs include the need for monitoring through blood testing, drug interactions, and narrow therapeutic windows. These shortcomings have led to the development of direct oral anticoagulants. These new oral agents…

Posted in: anticoagulation 12 direct oral anticoagulants 2 venous thromboembolism 5
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