Original Article

Tolerability of Switch to Macitentan from Bosentan in Pulmonary Arterial Hypertension

Objectives: Pulmonary arterial hypertension (PAH) is a progressive disease that can be treated with several medications. Macitentan, an endothelin receptor antagonist (ERA), has received approval as a PAH therapy. We report our data regarding the tolerability in patients with PAH who were switched from bosentan to macitentan. Methods: At the…