Original Article

Association between Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers and Lung Cancer

Objectives: Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are the most commonly prescribed antihypertensives, with prior studies identifying a possible association between long-term use and increased rates of lung cancer. This study evaluated this potential association in a large population using propensity matching. Methods: This was a population-based…

Posted in: angiotensin-converting enzyme inhibitors 4 lung cancer 19 propensity score 2

Review Article

Renin-Angiotensin-Aldosterone System (RAAS) Inhibitors and Coronavirus Disease 2019 (COVID-19)

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the virus responsible for the coronavirus disease 2019 (COVID-19) pandemic. The angiotensin-converting enzyme 2 (ACE2) has been proven to be used by SARS-CoV-2 for host cell entry. Considering that angiotensin receptor blockers and ACE inhibitors (ACEIs) upregulate the expression of ACE2 in animal…

Posted in: angiotensin receptor blockers 4 angiotensin-converting enzyme inhibitors 4 COVID-19 55

Review Article

The Pleiotropic Effects of Antihypertensive Agents: Do They Account for Additional Cardiovascular Benefit Beyond BP Reduction?

Hypertension commonly clusters with other cardiovascular risk factors, giving rise to the concept that hypertension is a multifaceted disease that potentially shares common pathogenic pathways with other risk factors. The renin-angiotensin-aldosterone system has a central role in the shared mechanisms of hypertension and cardiovascular disease, primarily through angiotensin II. Increased…

Posted in: angiotensin-converting enzyme inhibitors 4 Cardiovascular Disease 27 Hypertension 41

Expired CME Article

Proteinuria and Microalbuminuria in Adults: Significance, Evaluation, and Treatment

Expired CME Article – Proteinuria and Microalbuminuria in Adults: Significance, Evaluation, and Treatment

Posted in: angiotensin receptor blockers 4 angiotensin-converting enzyme inhibitors 4 chronic kidney disease 13 proteinuria 4
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