Original Article

Are Salt Tablets Effective in the Treatment of Euvolemic Hyponatremia?

Objectives: There is limited evidence for the use of salt tablets in the treatment of hyponatremia. This retrospective study evaluated the effectiveness of salt tablet administration in euvolemic hyponatremia.Methods: This was a single-center, retrospective cohort study. Information on patients’ demographics, clinical characteristics, and laboratory data were collected for retrospective review….

Posted in: hyponatremia 6

CME Topic

Diagnosis of the Syndrome of Inappropriate Secretion of Antidiuretic Hormone

Background:Hyponatremia is a frequent condition in elderly patients. In diagnostic workup, a 24-hour urine sample is used to measure urinary osmolality and urinary sodium concentration necessary to confirm the diagnosis of the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). This study was undertaken to test the hypothesis that a…

Posted in: elderly 20 hyponatremia 6

Case Report

A Challenging Case of Syndrome of Inappropriate Secretion of Antidiuretic Hormone in an Elderly Patient Secondary to Quetiapine

Hyponatremia secondary to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is an uncommon complication of treatment with centrally acting drugs including selective serotonin reuptake inhibitors (SSRIs) and antipsychotic medications. Antipsychotics are commonly used for the treatment of behavioral and psychiatric symptoms in elderly patients with dementia, and the…

Posted in: elderly 20 hyponatremia 6 quetiapine 3

Case Report

New Anticonvulsants-New Adverse Effects

Abstract:Ongoing refinements in pharmacology continue to provide new medications for the treatment of seizure disorders and other neurologic conditions. The authors present the cases of two children who developed relatively uncommon adverse effects to new anticonvulsant medications, including metabolic acidosis with topiramate and hyponatremia with oxcarbazepine. In one of our…

Posted in: hyponatremia 6 metabolic acidosis 2

Case Report

Water Intoxication Presenting as a Suspected Contaminated Urine Sample for Drug Testing

A patient was evaluated medically after submitting a urine sample for drug screening that was considered inappropriately dilute. Although it was thought that the dilute urine was the result of purposely adding water, the medical evaluation revealed that the patient had chronic water intoxication from a very strict weight loss…

Posted in: hyponatremia 6

Case Report

Nicotine Replacement Therapy-associated Syndrome of Inappropriate Antidiuretic Hormone

Nicotine has been documented to regulate the release of plasma arginine vasopressin (AVP). The literature is inconclusive about the effects of nicotine replacement therapy on AVP release, although cigarette smoking has been shown to increase the release of AVP. No clinical case reports have documented the possible association between nicotine…

Posted in: hyponatremia 6 smoking 10
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