Original Article

CME Article: Symptomatic Avascular Necrosis: An Understudied Risk Factor for Acute Care Utilization by Patients with SCD

Objectives: Sickle cell disease (SCD) is associated with high healthcare utilization rates and poor outcomes in a subset of patients, although the underlying factors that predict this phenotype are poorly understood. Prior studies suggest that comorbid avascular necrosis (AVN) contributes to high healthcare utilization. We sought to clarify whether AVN…

Posted in: avascular necrosis 2 hospitalization 14 osteonecrosis 4 sickle cell disease 28 utilization 2

Review Article

CME Article: Osteonecrosis in Sickle Cell Disease

Osteonecrosis is one of the most devastating musculoskeletal manifestations of sickle cell disease and most commonly affects the femoral head. Although the exact pathophysiology of this condition in patients with sickle cell disease is unknown, it is suggested that red cell sickling and repetitive vaso-occlusion may be associated with tissue…

Posted in: avascular necrosis 2 osteonecrosis 4 sickle cell disease 28
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