Review Article

A Narrative Review of the Pathophysiology and Treatment of Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is a genetic autosomal dominant disorder of the heart muscle that is characterized by left ventricular hypertrophy and sudden cardiac death. It is the most common inherited cardiac disease. HCM is defined by sarcomeric mutations that result in fibrosis of the heart, affecting contraction. In most cases,…

Posted in: cardiac hypertrophy 2 heart failure 21 hypertrophic cardiomyopathy 3 sudden cardiac death 5

Case Report

Uncommon Cause of a Common Disease

Myocardial infarction is a common life-threatening condition. Multiple agents can be used to treat acute coronary syndrome (ACS). These therapeutic agents pose potential life-threatening complications when used outside the realm of the acute coronary syndrome. Hypertrophic cardiomyopathy (HCM) is a common inherited cardiac disorder, occurring in 1 in 500 individuals,…

Posted in: Atrial Fibrillation 13 hypertrophic cardiomyopathy 3 myocardial infarction 15

Case Report

Improvement in Hypertrophic Cardiomyopathy after Significant Weight Loss: Case Report

A 17-year-old obese boy found to have familial apical hypertrophic cardiomyopathy on routine screening was enrolled in a weight loss program on the basis of the hypothesis that significant weight loss would improve his cardiac status. He was followed with serial dual-energy x-ray absorptiometry, electrocardiography, echocardiography, and blood pressure and…

Posted in: cardiac hypertrophy 2 Hypertension 39 hypertrophic cardiomyopathy 3 Obesity 70 weight loss 13
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