Review Article

Safety of Baricitinib 4 mg for the Treatment of Moderate to Severe Rheumatoid Arthritis

Objective: We evaluated the safety of baricitinib 4 mg at 24 weeks for the treatment of moderate to severe rheumatoid arthritis (RA). Methods: Multiple databases were searched from inception up to November 26, 2019 for randomized controlled trials comparing baricitinib 4 mg with placebo for the treatment of moderate to…

Posted in: meta-analysis 5 rheumatoid arthritis 12

Review Article

Battlefield Acupuncture: Is It Ready for Widespread Dissemination?

The use of prescription opioids for chronic pain has increased markedly within the past few decades; thus, death rates associated with opioid overdoses have increased dramatically. Nonopioid pharmacologic therapies also are associated with adverse effects. Other pain-abatement modalities such as acupuncture may be useful in the treatment of several painful…

Posted in: acupuncture 5 alternative medicine 3 integrative medicine 4 meta-analysis 5 pain 18

Original Article

Effects of Statin Therapy in Patients with Systemic Lupus Erythematosus

Objectives: Systemic lupus erythematosus (SLE) is associated with a significant risk of cardiovascular mortality. The use of statins for lipid modulation and the prevention of cardiovascular disease in this population also may impart pleiotropic anti-inflammatory and immunomodulatory effects. Our aim was to identify studies that compared the use of statins…

Posted in: meta-analysis 5 Statins 8 systemic lupus erythematosus 9

Original Article

Effects of Vitamin D Supplementation on Blood Pressure

Objective: Inconsistent findings from epidemiological studies have continued the controversy over the role of oral vitamin D supplementation in reducing blood pressure in normotensive or hypertensive populations. Methods: We performed a literature search up to December 2009, with no restrictions. Only double-blind randomized controlled trials (RCTs) of oral vitamin D…

Posted in: blood pressure 10 meta-analysis 5 vitamin D 17

Original Article

Prophylactic Antibiotics in Necrotizing Pancreatitis: A Meta-analysis

Purpose: Prophylactic antibiotics have been used in acute necrotizing pancreatitis with mixed results. This meta-analysis analyzes the effects of prophylactic antibiotics in necrotizing pancreatitis. Methods: Multiple databases and abstracts were searched for randomized trials comparing treatment with prophylactic antibiotics to treatment without prophylactic antibiotics in necrotizing pancreatitis. Prophylactic antibiotics’ effects…

Posted in: meta-analysis 5 pancreatitis 16 randomized controlled trials 2
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