Objectives: Neural tube defects (NTDs) are one of the most common major birth defects, yet the reasons for occurrence of many NTDs are still not well understood. This study sought to determine the presence of seven specific NTD risk factors in a sample of 515 isolated NTD cases that occurred…
Background: Laboratory evidence is presented of significant associations between reduced maternal serum folate and vitamin B12 levels and neural tube birth defects (NTD) compared to referents. Methods: This was an incident case-control study. Cases of neural tube defects (including anencephaly and open spina bifida) diagnosed in residents within 100 miles…
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