Original Article

Overuse of Acid-Suppression Therapy at an Urban Tertiary Hospital

Objectives: Acid-suppressive therapy (AST) is widely used for gastrointestinal prophylaxis in hospitalized patients, particularly to prevent stress-related mucosal bleeding in critically ill individuals. Previous reports suggest gross overutilization and continuation of unnecessary therapy, which have been linked to several adverse effects. Methods: Retrospective chart review at a large tertiary care…

Posted in: clinical practice guidelines 2 nonsteroidal anti-inflammatory drugs 2 proton pump inhibitors 7

Case Report

Recovery Time in a Case of Gemfibrozil and Simvastatin-Associated Rhabdomyolysis

Abstract:Simvastatin is a cholesterol-lowering medication heavily prescribed to treat and prevent vascular disease. Despite widespread use, cases of simvastatin-induced rhabdomyolysis are rare. Little information is available regarding the recovery period for a patient who has experienced drug-induced rhabdomyolysis. We present a case involving a patient with multiple risk factors (advanced…

Posted in: nonsteroidal anti-inflammatory drugs 2 rhabdomyolysis 8
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