Original Article

Awareness and Indications of 5-α-Reductase Inhibitors for Benign Prostatic Hyperplasia in the Primary Care Setting

Objective: The objective of the study was to investigate primary care physicians’ (PCPs’) level of awareness and indications for urology referral in patients treated with 5-α-reductase inhibitors (5-ARIs). Methods: An anonymous 14-question survey was e-mailed to PCPs in the specialties of Family Medicine and Internal Medicine at an academic institution….

Posted in: primary health care 3 prostate cancer 7 prostate-specific antigen 3

Review Article

Androgen Deprivation Therapy/Androgen Receptor Signaling Inhibitor Treatments for Prostate Cancer: Pathophysiology and Review of Effects on Cardiovascular Disease

Androgen deprivation therapy is the cornerstone of systemic management for prostate cancer but is associated with multiple adverse effects that must be considered during treatment. These effects occur because of the profound hypogonadism that is induced from lack of testosterone or due to the medications used in the treatment or…

Posted in: prostate cancer 7

Original Article

OPEN: Initial Institutional Experience with 18F-Fluciclovine PET-CT in Biochemical Recurrence of Prostate Cancer

Objectives: 18F-fluciclovine (fluciclovine) is an amino acid analog approved by the Food and Drug Administration for use as a radiotracer in positron emission tomography (PET) in men with biochemical recurrence of suspected prostate cancer. The purpose of this study was to investigate the initial institutional experience with 18F-fluciclovine in the…

Posted in: prostate cancer 7

Original Article

Effects of Commercially Available Soy Products on PSA in Androgen-Deprivation-Naïve and Castration-Resistant Prostate Cancer

Objective: No standard therapeutic option exists for men with prostate cancer who have failed local therapy, have no gross metastatic disease, and whose only manifestation of disease is a rising prostate-specific antigen (PSA) level. Soy products are able to affect PSA kinetics in some men with prostate cancer, and this…

Posted in: prostate cancer 7 prostate-specific antigen 3

Original Article

Socioeconomic Disparities in Prostate Cancer Mortality and the Impact of Geographic Scale

Objective: To examine socioeconomic disparities in prostate cancer mortality and to assess the scale effect on the results of the disparity analysis. Methods: Using prostate cancer mortality data (N = 14,036) of Texas from 1996 to 2004, this study examines the variations of socioeconomic disparities in prostate cancer mortality across…

Posted in: cancer disparity 2 prostate cancer 7 socioeconomic status 7

Case Report

Drug-Induced Liver Injury Caused by the Histrelin (Vantus®) Subcutaneous Implant

Drug-induced liver injury (DILI) is the leading cause of acute hepatic failure in the United States. Up to 13% of acute liver failure cases occur due to drugs other than acetaminophen. This clinical diagnosis, made after other causes of liver injury have been excluded, requires establishing a causal relationship between…

Posted in: drug induced liver injury 2 prostate cancer 7

Case Report

Metastatic Prostatic Carcinoma Presenting as Fulminant Hepatic Failure

A 68-year-old male presented with progressive abdominal pain, dyspnea, weight loss, and dysuria. Lab work revealed elevated creatine phosphokinase levels, prostate-specific antigen level (approximately 60 ng/mL), and elevated liver enzymes. He was admitted to the intensive care unit for worsening respiratory distress and confusion. He continued to deteriorate, and his…

Posted in: prostate cancer 7
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