Review Article

Diabetes Mellitus and the Skin: Recognition and Management of Cutaneous Manifestations

Diabetes mellitus (DM) is a heterogeneous condition characterized by hyperglycemia as a consequence of defects in insulin secretion and variable degrees of insulin resistance. DM is the most common endocrine disorder in the United States, affecting 9.3% of the population (29.1 million people) in 2014. Skin disorders are present in…

Posted in: acanthosis nigricans 2 Dermatology 3 diabetes mellitus 34

Case Report

Bilateral Leser-Trélat Sign Mirroring Lung Adenocarcinoma with Early Metastases to the Contralateral Lung

Abstract:We present a case featuring a unique overlap between the body areas involved by lung adenocarcinoma and the cutaneous paraneoplastic sign of Leser-Trélat. In our patient, the Leser-Trélat sign consisted of explosive multiple seborrheic keratoses in combination with acanthosis nigricans, representing a remarkable geometric skin projection of lung cancer which…

Posted in: acanthosis nigricans 2
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