CME Topic

Adverse Cutaneous Reactions Induced by TNF-&agr; Antagonist Therapy

Objective:To review adverse cutaneous drug reactions induced by tumor necrosis factor alpha (TNF-&agr;) antagonist therapy.Methods:A literature search was performed using PubMed (1996–March 2009), EMBASE, and selected MEDLINE Ovid bibliography searches. All language clinical trial data, case reports, letters, and review articles identified from the data sources were used.Results:Since the introduction…

Posted in: adalimumab 2 adverse drug reaction 6 etanercept 3 infliximab 4 tumor necrosis factor 2

Case Report

Adalimumab-Induced Acute Myelogenic Leukemia

Newer biological treatment strategies have been developed in the last decade with some promising outcomes. Their safety, however, has been questioned lately with multiple reports of increased risk for malignancies and infectious complications. These reports render their use suboptimal. We report a 44-year-old woman receiving adalimumab (Humira®) for advanced juvenile…

Posted in: acute myeloid leukemia 2 adalimumab 2 dysplasia 2
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