SMJ articles in the category "biomarkers"

Original Article

Differences in Cardiometabolic Biomarkers between Elementary School–Age Latinx Children with Obesity versus Healthy Weight

Objectives: Low-income Latinx youth are disproportionately affected by obesity, which results in an increased risk of cardiometabolic abnormalities. Biomarker tracking may be useful for the early identification of obesity comorbidities in young Latinx children. Hence, we aimed to compare cardiometabolic biomarkers between age- and sex-matched pairs of elementary school-aged Latinx…

Posted in: biomarkers 4 Childhood 2 health disparities 20 Obesity 71

Review Article

Serum Biomarkers for Traumatic Brain Injury

There is a lack of reliable serum biomarkers for routine use in the diagnostic workup of people with traumatic brain injury. Multiple biomediators and biomarkers have been described in the pertinent literature in recent years; however, only a few candidate molecules have been associated with high sensitivity and high specificity…

Posted in: biomarkers 4 risk stratification 4 traumatic brain injury 2

Review Article

Investigational Biomarkers for Pancreatic Adenocarcinoma: Where Do We Stand?

Although the outcomes for pancreatic ductal adenocarcinoma (PDAC) remain disappointing, there has been considerable improvement in the 5-year survival rate of patients with resectable disease. As such, an R0 surgical resection (microscopic tumor clearance) offers patients with PDAC the greatest survival benefit. Carbohydrate antigen 19-9, the only US Food and…

Posted in: biomarkers 4 pancreatic cancer 6

Review

Challenge of Surrogate Endpoints

Surrogate endpoints are biomarkers that are intended to substitute for clinical endpoints. They have been used to find novel therapeutic targets, improve the statistical power and shorten the duration of clinical trials, and control the cost of conducting research studies. The more generalized use of surrogate endpoints in clinical decision…

Posted in: biomarkers 4 evidence-based medicine 18 Special Issue 75
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