SMJ articles in the category "Crohn disease"

Original Article

Systematic Review and Meta-Analysis: Preoperative Vedolizumab and Postoperative Complications in Patients with IBD

Objectives: The effect of vedolizumab on postoperative outcomes in patients with inflammatory bowel disease (IBD) remains unclear. We aimed to determine the relation between preoperative vedolizumab and early postoperative complications in patients with IBD undergoing abdominal surgery. Methods: A search of databases and abstracts from gastroenterology conferences was performed. Primary…

Posted in: Crohn disease 5 inflammatory bowel disease 10 postoperative complications 6 ulcerative colitis 6

Review Article

Upper Gastrointestinal Involvement in Crohn Disease: Histopathologic and Endoscopic Findings

Objectives: Studies describing the prevalence of upper gastrointestinal (GI) Crohn disease (CD) and its histopathologic changes have been inconsistent as a result of different definitions used for upper GI involvement, diverse populations, and varying indications for endoscopy. We reviewed the literature describing endoscopic findings and histologic lesions in gastric and…

Posted in: Crohn disease 5 upper endoscopy 2

Original Article

pANCA Positivity Predicts Lower Clinical Response to Infliximab Therapy among Patients with IBD

Objectives: Several studies have been performed evaluating the role of perinuclear anti-neutrophil cytoplasmic antibodies (pANCA) to predict early clinical response among patients with inflammatory bowel disease (IBD) who are undergoing infliximab therapy. The results of these studies are variable, however, and the effect of pANCA+ as a predictor of clinical…

Posted in: Crohn disease 5 inflammatory bowel disease 10 infliximab 4 ulcerative colitis 6

Expired CME Article

Crohn Disease of the Esophagus: A Review of the Literature

Esophageal Crohn disease is a difficult disease both to diagnose and treat. The diagnosis is made in patients with other extraintestinal manifestations of Crohn disease in whom other esophageal pathology has been ruled out. This often requires integration of clinical, endoscopic, radiographic, and histologic findings. Despite its relative rarity, it…

Posted in: Crohn disease 5 esophagitis 2 stent 5

Case Report

Successful Treatment of Severe Gastrointestinal Bleeding Secondary to Crohn Disease with Recombinant Factor VIIa

A 58-year-old man diagnosed with ileocolonic Crohn disease was admitted to the emergency room with massive lower gastrointestinal hemorrhage and hypovolemic shock. Treatment was started with methylprednisolone, metronidazole and omeprazole. Within the next 24 hours, he received a total of 9 U of red blood cell concentrate and 2 U…

Posted in: bleeding 6 Crohn disease 5 hemorrhage 7 recombinant factor VIIa 2 surgery 23
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