Review

Emergence of Klebsiella pneumoniae Carbapenemase-Producing Bacteria

Klebsiella pneumoniae carbapenemase (KPC)-producing bacteria are a group of emerging highly drug-resistant Gram-negative bacilli causing infections associated with significant morbidity and mortality. Once confined to outbreaks in the northeastern United States (US), they have spread throughout the US and most of the world. KPCs are an important mechanism of resistance…

Posted in: Enterobacteriaceae 2

Original Article

Klebsiella pneumoniae Carbapenemase-Producing Enterobacteriaceae, Northeast Florida

Background:Since 2001 there have been several reported outbreaks due to carbapenem-resistant Klebsiella pneumoniae (Kp), particularly in the northeastern states.Methods:Carbapenemase-producing Enterobacteriaceae from healthcare facilities in Northeast Florida were phenotypically identified and confirmed using PCR amplification and sequencing of the blaKPC gene.Results:Results from PFGE analysis of these isolates demonstrated possible horizontal spread…

Posted in: Enterobacteriaceae 2
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