Case Report

Idiopathic Hypereosinophilic Syndrome: A Rare but Fatal Condition Presenting with Common Symptoms

Introduction: Idiopathic hypereosinophilic syndrome (IHES) is a leukoproliferative disorder characterized by cytokine-induced overproduction of eosinophils with resultant multiorgan infiltration and damage. The diagnostic criteria includes evidence of end organ damage, exclusion of all other causes of eosinophilia and sustained absolute eosinophil count (AEC) > 1,500 cells/mcl for at least 6…

Posted in: eosinophilia 4 hypereosinophilic syndrome 2

Review Article

Hypereosinophilic Syndrome: Two Case Reports of Contrasting Variants

Two cases of hypereosinophilic syndrome that illustrate different variants are reported. Recognition of the specific variant is important because the treatments differ. Patients with hypereosinophilic syndrome should be monitored for evidence of a myeloproliferative process because treatment with tyrosine kinase inhibitors in these patients is effective and may prevent significant…

Posted in: hypereosinophilic syndrome 2 tyrosine kinase inhibitor 2
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