Original Article

Comparing the Aspartate Aminotransferase (AST) to Platelet Ratio Index (APRI) Between African American and White Veterans with Chronic Hepatitis C

Objectives: The study of noninvasive markers of fibrosis, such as aspartate aminotransferase (AST) to platelet ratio index (APRI), have been limited in African American populations. Given the disparate outcomes of chronic hepatitis C in African American populations, comparative analyses of the APRI score should be undertaken. Compare the diagnostic accuracy…

Posted in: African Americans 8 healthcare disparities 4 hepatitis C 15 liver disease 4

Expired CME Article

Hepatorenal Syndrome

Acute kidney injury (AKI) secondary to hepatorenal syndrome (HRS) is an ominous complication of end-stage liver disease (ESLD). In HRS, splanchnic and peripheral vasodilatation with reduction in effective arterial volume causes activation of mechanisms leading to intense renal vasoconstriction and functional AKI. HRS is a diagnosis of exclusion and all…

Posted in: acute 7 injury 10 kidney 5 liver disease 4

Case Report

Celiac Sprue Presenting as Advanced Liver Disease

This case report describes the complexity of diagnosing celiac sprue in a patient who presented with features predominantly resembling that of advanced liver disease in the absence of diarrhea. Key Points * Highly variable clinical presentations make the diagnosis of celiac sprue challenging. * The association between celiac sprue and…

Posted in: liver disease 4 small intestine 4

Review Article

Hepatitis C Infection: A Clinical Review

Nearly three million persons in the United States are viremic with hepatitis C (HCV). Despite a decreasing incidence of HCV in this country, the prevalence of HCV-related chronic liver disease is increasing. Most infections in the United States are acquired by intravenous drug use. The chronicity rate of HCV is…

Posted in: hepatitis C 15 liver disease 4 pegylated interferon 2
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