Case Report

Plasma Cell Leukemia Presenting as Organizing Pneumonia Refractory to High-Dose Steroid Therapy

A case of steroid-refractory organizing pneumonia (OP) as the initial presentation of plasma cell leukemia (PCL) in a patient who had no prior exposure to chemotherapy or radiation is described. Since OP is traditionally a steroid-responsive disease, this case raises the possibility of a previously unknown patient subgroup with variable…

Posted in: multiple myeloma 10 organizing pneumonia 2 plasma cell leukemia 2

Case Report

Thalidomide-induced Organizing Pneumonia

Twenty medications are associated with drug-induced organizing pneumonia; however, thalidomide is not listed as a potential causative agent. Thalidomide (Thalomid, Celgene Corp., Summit, NJ), an angiogenesis inhibitor and immunomodulator that reduces tumor necrosis factor-alpha, is used for the treatment of multiple myeloma. We report a case of organizing pneumonia in…

Posted in: multiple myeloma 10 organizing pneumonia 2 pulmonary toxicity 3 thalidomide 2
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