Original Article

Incidence and Impact of False-Positive Urine Pneumococcal Antigen Testing in Hospitalized Patients

Objectives: Immunochromatographic urine pneumococcal antigen testing (ICT) has become a common diagnostic tool for those presenting with possible invasive pneumococcal disease. The incidence and clinical impact of ICT false-positivity on hospitalized patients has not been assessed outside of specific patient subpopulations. ICT performance needs to be assessed in a real-world…

Posted in: Streptococcus pneumoniae 6

Case Report

Acute Epidural Abscess Complicating Pneumococcal Meningitis in Adult

Acute spinal epidural abscesses rarely complicate bacterial meningitis in adults. We report an uncommon case of advanced pneumococcal meningitis complicated by acute lumbar epidural abscess in an adult. A 35-year-old man was admitted to the medical intensive care unit with pneumococcal meningitis. On the eighth day of hospitalization, he presented…

Posted in: Adult 5 bacterial meningitis 3 complications 13 Streptococcus pneumoniae 6

Case Report

Streptococcus pneumoniae Septic Arthritis Complicating Hip Osteonecrosis in Adults: Case Report and Review of the Literature

A 42-year-old patient presented acutely with bacteremic pneumococcal pneumonia along with metastatic pneumococcal infection of the hip joint. Diagnostic evaluation revealed evidence of a pre-existing bilateral hip osteonecrosis. The osteonecrotic changes were attributed to chronic alcohol abuse and/or an old motor vehicle accident. Appropriate therapy was promptly instituted and the…

Posted in: hip joint 2 infectious arthritis 2 osteonecrosis 4 Streptococcus pneumoniae 6

Original Article

Statewide Sentinel Surveillance for Antibiotic Nonsusceptibility among Streptococcus pneumoniae Isolates in South Carolina, 2003–2004

Background: In 2003, the South Carolina Department of Health and Environmental Control established the Carolina Antibiotic Resistance Surveillance System (CARSS), an active sentinel surveillance system for antibiotic-resistant Streptococcus pneumoniae. Methods: CARSS includes twelve hospitals. Each hospital was assigned a weighted sample size. Minimum inhibitory concentrations were determined using the E-test…

Posted in: antibiotic resistance 4 Streptococcus pneumoniae 6 surveillance 14

Case Report

Evolving Infectious Aortitis Caused by Streptococcus pneumoniae

Infections of major vessels leading to mycotic aneurysms can be a diagnostic dilemma for clinicians, and can be accompanied by a high mortality rate. Successful treatment of this condition often requires a high index of suspicion and prompt medical and surgical attention. The authors report two cases of infectious aortitis…

Posted in: Streptococcus pneumoniae 6

Original Article

Laboratory Survey of Antibiotic Nonsusceptibility among Streptococcus pneumoniae Isolates in South Carolina, 1998 versus 2000

Background In 1998, the South Carolina Department of Health and Environmental Control surveyed clinical microbiology laboratories statewide to determine the prevalence of antibiotic nonsusceptibility among isolates of Streptococcus pneumoniae. A follow-up study was conducted in 2001. Methods A cross-sectional study was conducted to estimate the prevalence of penicillin nonsusceptibility (PCN-N),…

Posted in: antibiotic resistance 4 Streptococcus pneumoniae 6 surveillance 14
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