SMJ articles in the category "thrombotic microangiopathy"

CME Topic

Thrombotic Thrombocytopenic Purpura: The Masquerader

Abstract:Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disorder with a mortality rate of up to 90% if left untreated, and is characterized by microvascular thrombi, mainly in small arteries and capillaries, thrombocytopenia, hemolysis, and neurological abnormalities. Malignant hypertension (HTN) is a clinical syndrome characterized by severe hypertension associated with end-organ…

Posted in: microangiopathic hemolytic anemia 2 thrombotic microangiopathy 3 thrombotic thrombocytopenic purpura 6

Case Report

Thrombotic Microangiopathy as a Complication of Medicinal Leech Therapy

Medicinal leeches (hirudo medicinalis) are increasingly used as a useful therapeutic option in various medical and surgical settings. The potential complications associated with this therapy include infections with Aeromonas species, bleeding, anemia, and allergic reactions. We describe a patient who developed thrombotic microangiopathy and acute renal failure following leech therapy….

Posted in: renal failure 10 thrombotic microangiopathy 3

Case Report

The Spectrum of Thrombotic Thrombocytopenic Purpura: A Clinicopathologic Demonstration of Tacrolimus-Induced Thrombotic Thrombocytopenic Purpura in a Lung Transplant Patient

Immunosuppressive drugs used post-transplantation are among the most common causes of thrombotic thrombocytopenic purpura (TTP). Diagnosis is often confounded not only by its myriad presentations, but also because these manifestations may be explained by the comorbidities or complications of transplantation. A 61-year-old female who had a single lung transplant for…

Posted in: lung transplant 2 thrombotic microangiopathy 3 thrombotic thrombocytopenic purpura 6
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