Original Article

Factors Associated with Recently Transmitted Mycobacterium tuberculosis Strain MS0006 in Hinds County, Mississippi

Objective: The objective of this study was to investigate risk factors associated with tuberculosis (TB) transmission that was caused by Mycobacterium tuberculosis strain MS0006 from 2004 to 2009 in Hinds County, Mississippi. Methods: DNA fingerprinting using spoligotyping, mycobacterial interspersed repetitive unit, and IS6110-based restriction fragment length polymorphism of culture-confirmed cases…

Posted in: HIV 30 Mississippi 7 tuberculosis 13

Original Article

Challenges and Opportunities in a Tuberculosis Outbreak Investigation in Southern Mississippi, 2005-2007

Objective: Between December 2005 and November 2007, a cluster of 11 tuberculosis (TB) cases emerged in Jackson County, Mississippi. We investigated the potential sources of disease transmission and epidemiologic links in this cluster to prevent future transmission in the community. Materials and Methods: Cases of TB reported in Jackson County…

Posted in: epidemiology 36 Mississippi 7 outbreak 2 tuberculosis 13

Case Report

False-Positive Amplified Mycobacterium tuberculosis Direct Tests in Skin Specimens of Leprosy

The amplified Mycobacterium tuberculosis (M tuberculosis) direct test (MTD) is reported to be a highly sensitive (92.6%) and specific (100%) test for the detection of M tuberculosis. We report two cases of human leprosy in which false-positive amplified MTD testing on skin biopsies led to initial misdiagnoses of cutaneous M…

Posted in: leprosy 4 Mycobacteria 2 tuberculosis 13

Case Report

Clavicular Tuberculosis Following Trivial Trauma

Abstract:Tuberculosis of the clavicular bone is a very rare clinical entity, with limited cases reported in the United States. Furthermore, sparing of the sternoclavicular joint is exceedingly unusual. A literature review of the prevalence of clavicular tuberculosis identified fewer than 80 cases reported since the discovery of the tubercular bacillus,…

Posted in: trauma 24 tuberculosis 13

Case Report

Waxing and Waning Pulmonary Nodules and Myelodysplastic Syndrome

Abstract:A 53-year-old diabetic woman with the diagnosis of myelodysplastic syndrome was admitted to our hospital with symptoms of anorexia, malaise, fatigue, night sweats, and weight loss. The radiological evaluation revealed waxing and waning pulmonary nodules. A diagnosis of pulmonary tuberculosis was reached by pathologic examination of a wedge biopsy. We…

Posted in: myelodysplastic syndrome 2 tuberculosis 13

Case Report

Vitamin D as Adjunctive Therapy in Refractory Pulmonary Tuberculosis: A Case Report

Abstract:Vitamin D regulates calcium homeostasis in the body and may play a major role in regulating immune responses to tuberculosis (TB). Pilot studies suggest that vitamin D supplementation may improve outcomes in pulmonary TB (PTB), but clinical evidence using vitamin D in TB treatment is limited. We present a case…

Posted in: immunity 2 Treatment 22 tuberculosis 13 vitamin D 17

Original Article

A Cross-Sectional Study of HIV and Tuberculosis Coinfection Cases in Mainland China

Background: The prevalence of HIV/AIDS and tuberculosis (TB) within mainland China is unprecedented and the convergence of these two infectious diseases is increasingly and significantly endangering human health for socioeconomic development. To date, the clinical manifestations, laboratory presentation, and epidemiologic features of HIV/TB coinfection cases in mainland China have not…

Posted in: HAART 4 HIV/AIDS 3 tuberculosis 13

Case Report

Primary Tuberculous Liver Abscess: A Case Report and Review of the Literature

Abstract:A 48-year-old diabetic man was admitted to our hospital with abdominal pain in the right upper quadrant, weight loss, night sweats, fatigue, and anorexia. Ultrasonography, computed tomography, and magnetic resonance imaging of the abdomen revealed multiple hemangiomas and a hypodense mass lesion in the posterior segment of the right hepatic…

Posted in: liver abscess 3 tuberculosis 13

Case Report

Active Pulmonary Tuberculosis with Vertebra and Rib Involvement: Case Report

Multifocal skeletal tuberculosis is defined as osteoarticular lesions that occur simultaneously at two or more locations and is generally associated with disseminated disease. Although involvement of bones accounts for 1 to 5% of all tuberculosis cases, multifocal involvement of the skeleton is extremely rare. We present a case of active…

Posted in: tuberculosis 13

Case Report

Methicillin-resistant Staphylococcus aureus Empyema Necessitatis in an Eight-month-old Child

Empyema necessitatis is a rare complication of empyema characterized by a spontaneous extension of pus from the pleural space into adjacent soft tissues. It is uncommon in the pediatric population and is usually caused by Mycobacterium tuberculosis. This report describes the youngest reported case of empyema necessitatis. The clinical examination…

Posted in: methicillin-resistant Staphylococcus aureus 6 pleural effusion 9 pneumonia 14 tuberculosis 13

Case Report

Kaposi Sarcoma Secondary to Pulmonary Tuberculosis: A Rare Case

Kaposi sarcoma commonly occurs in HIV-positive and immunocompromised patients. We describe a case of Kaposi sarcoma that developed in an HIV-negative patient with tuberculosis. The Kaposi sarcoma completely regressed with antituberculous therapy without the institution of chemotherapy. The patient remained disease-free after a follow-up period of 20 months. Patients with…

Posted in: kaposi sarcoma 3 tuberculosis 13

Case Report

Multifocal Skeletal Tuberculosis

Multifocal skeletal tuberculosis is defined as osteoarticular lesions that occur simultaneously at two or more locations. We present radiologic findings in two cases of multifocal osteoarticular tuberculosis. Differential diagnoses of such lesions, based on different radiologic modalities, can include metastatic disease, eosinophilic granuloma, or lymphoma. Since tuberculosis can be present…

Posted in: magnetic resonance imaging 13 tuberculosis 13

Case Report

Simultaneous Occurrence of Hodgkin Disease and Tuberculosis: Report of Three Cases

Tuberculosis (TB) has been described in association with malignancies including Hodgkin disease (HD). We report three cases of simultaneous occurrence of TB and HD. In two of these cases clinical symptoms improved after TB treatment was instituted and before HD was diagnosed. Fever recurrence in one case and persistence of…

Posted in: Hodgkin disease 2 immunohistochemistry 3 lymph nodes 2 tuberculosis 13
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