SMJ articles in the category "Helicobacter pylori"

Original Article

Helicobacter pylori Eradication Rates among Patients Undergoing Endoscopy Remain Stagnant Despite Evolving Clinical Practice Patterns

Objectives: Helicobacter pylori is the strongest risk factor for non-cardia gastric adenocarcinoma, the cancer with the greatest racial disparity in US cancer mortality. The 2017 American College of Gastroenterology guidelines recognized that local H pylori antibiotic resistance data are often unavailable in the United States, highlighted increasing clarithromycin resistance, and…

Posted in: antibiotics 6 ECU 2 gastric cancer 4 Helicobacter pylori 10

Original Article

Type 2 Diabetes Mellitus and Helicobacter pylori Eradication in a Clinical Population

Objectives: Eradication of Helicobacter pylori reduces the risk of gastric cancer (GC). Individuals with type 2 diabetes mellitus (T2DM) are known to be at increased risk for GC. In a cohort of H. pylori-positive individuals, we assessed whether those with T2DM were at risk of persistent infection following H. pylori…

Posted in: diabetes mellitus 34 eradication 3 Helicobacter pylori 10 type 2 diabetes mellitus 13

Review Article

An Updated Approach to Evaluation and Treatment of Helicobacter pylori Infection

Helicobacter pylori is a chronic bacterial infection that can lead to peptic ulcer disease, chronic gastritis, and gastric cancer. Its prevalence in the United States is lower than in most of the world, although specific populations are at particular risk for disease-related complications, including those with lower socioeconomic status and…

Posted in: antibiotic resistance 4 Diagnosis 17 epidemiology 36 Helicobacter pylori 10

Review

Proton Pump Inhibitors: The Good, the Bad, and the Unwanted

Proton pump inhibitors (PPIs) are one of the most commonly prescribed classes of medications in the United States. By inhibiting gastric H+/K+ adenosine triphosphatase via covalent binding to the cysteine residues of the proton pump, they provide the most potent acid suppression available. Long-term PPI use accounts for the majority…

Posted in: clopidogrel 2 Helicobacter pylori 10 proton pump inhibitors 7

Original Article

Association of Helicobacter pylori Infection with the Development of Colorectal Polyps and Colorectal Carcinoma

Background and Aims: Recent studies have suggested a possible association between Helicobacter pylori (HP) infection and colon neoplasia. HP infection causes hypergastrinemia, and gastrin increases colorectal mucosal proliferation, potentially leading to colorectal cancer. We investigated whether HP infection is associated with colon neoplasia. Methods: We conducted a cross-sectional, single-center study…

Posted in: adenomatous polyps 2 colorectal cancer 17 Helicobacter pylori 10

Original Article

Relationship of the Intensity of Helicobacter pylori and Severity of Inflammation with Beta-2 Microglobulin Levels in Serum According to the Updated Sydney System

Objective: Helicobacter pylori (HP) is a cause of chronic gastritis. Beta-2 microglobulin has been used as a simple inflammatory indicator in some diseases. We investigate the usability of beta-2 microglobulin as a simple marker that may reflect the severity of inflammation and intensity of HP in gastric mucosa. Materials and…

Posted in: gastritis 2 Helicobacter pylori 10

Original Article

Effect of Sequential Treatment as a First-Line Therapy for Helicobacter pylori Eradication in Patients with Diabetes Mellitus

Objectives: The Maastricht III Consensus agreed that effective treatment for Helicobacter pylori (HP) should achieve an intention-to-treat (ITT) eradication rate above 80%, which is still lacking in patients with type 2 diabetes mellitus (DM). This pilot study was designed to confirm the efficacy of a 14-day sequential treatment regimen in…

Posted in: Helicobacter pylori 10 type 2 diabetes 7

Original Article

Should Increased Levels of Urinary 8-Hydroxydeoxyguanosine in Chronic Gastritis Imply Intestinal Metaplasia or Gastric Atrophy?

Objectives: Helicobacter pylori (H pylori) infection induces chronic inflammation that can progress to gastric atrophy, intestinal metaplasia, and gastric adenocarcinoma. We have examined oxidative damage caused by Helicobacter pylori, metaplasia, and atrophy of gastric mucosal cells in patients with chronic gastritis by measuring their urinary 8-hydroxydeoxyguanosine (8-OHdG) levels. Methods: We…

Posted in: Helicobacter pylori 10 intestinal metaplasia 2

Original Article

Clarithromycin Resistance and Efficacy of Clarithromycin-Containing Triple Eradication Therapy for Helicobacter pylori Infection in Type 2 Diabetes Mellitus Patients

Background:Antimicrobial resistance in Helicobacter pylori infection is an important factor leading to failure of therapy. The aim of this study was to determine the eradication rate of H pylori in type 2 diabetes mellitus and to assess the effect of clarithromycin resistance on H pylori eradication.Method:Fifty-six consecutive patients with type…

Posted in: diabetes mellitus 34 eradication therapy 2 Helicobacter pylori 10

Original Article

Effect of N-Acetyl Cysteine on Helicobacter pylori

Background: Use of mucolytic agents that result in reduced mucous viscosity of the gastric mucous has been suggested to have an additive effect in curing Helicobacter pylori infection. Methods: Seventy H pylori–positive patients were given either eradication treatment consisting of 500 mg clarithromycin bid and 30 mg lansoprazole bid for…

Posted in: eradication therapy 2 Helicobacter pylori 10
SMA Menu