Original Article

Helicobacter pylori Eradication Rates among Patients Undergoing Endoscopy Remain Stagnant Despite Evolving Clinical Practice Patterns

Objectives: Helicobacter pylori is the strongest risk factor for non-cardia gastric adenocarcinoma, the cancer with the greatest racial disparity in US cancer mortality. The 2017 American College of Gastroenterology guidelines recognized that local H pylori antibiotic resistance data are often unavailable in the United States, highlighted increasing clarithromycin resistance, and…

Posted in: antibiotics 6 ECU 2 gastric cancer 4 Helicobacter pylori 10

Original Article

CME Article: Impact of β-Lactam Allergies on Antimicrobial Selection in an Outpatient Setting

Objective: The primary objective of this study was to determine whether patients prescribed nonpreferred antibiotics received appropriate alternative antibiotics.Methods: This was a retrospective observational analysis of military veteran patients with a β-lactam allergy treated in an outpatient clinic or emergency department for an infection during a 5-year span. Antibiotic regimens…

Posted in: adverse drug reaction 6 allergy 4 antibiotics 6 primary care 64

Review Article

Point-of-Care Sinus Ultrasound: Impact Within a Large Internal Medicine Clinic and Review of Technique

Outpatient diagnosis of acute bacterial sinusitis, using only traditional physical examination and clinical criteria, results in the overuse of antibiotics in patients with upper respiratory complaints. Point-of-care maxillary sinus ultrasound is easy to learn and quick to perform in a primary care clinic. The technique can reduce antibiotic prescribing by…

Posted in: antibiotics 6 internal medicine 16 POCUS 51 point-of-care ultrasound 18 sinusitis 5 Special Issue 75

Original Article

Variation in Use of Prophylactic Antibiotics in Gynecologic Procedures Before and After an Educational Intervention

Objectives: Guidelines for use of prophylactic antibiotics in gynecologic procedures are outlined by the American Congress of Obstetricians and Gynecologists. There remains, however, a high rate of unindicated administration of antibiotics for surgeries. A retrospective study performed at our institution in 2012–2013 demonstrated that unindicated prophylactic antibiotics were administered over…

Posted in: adverse events 6 antibiotics 6 gynecology 5 quality improvement 22

Original Article

Prophylaxis with Ertapenem in Patients with Obstructive Jaundice Undergoing Endoscopic Retrograde Cholangiopancreatography: Safety, Efficacy, and Biliary Penetration

Antibiotic prophylaxis before endoscopic retrograde cholangiopancreatography (ERCP) is primarily aimed at the prevention of cholangitis and secondary sepsis. Although these complications are uncommon, they are associated with considerable morbidity and, rarely, mortality. Despite the absence of strong level I evidence, the European Society of Gastrointestinal Endoscopy guidelines, published in 1999,…

Posted in: antibiotics 6 bilirubin 2 cholangiography 2

Original Article

Management of Infective Endocarditis in Outpatients: Clinical Experience with Outpatient Parenteral Antibiotic Therapy

Background:There is limited experience in treating infective endocarditis (IE) with outpatient parenteral antibiotic therapy (OPAT).Methods:Following institutional review board (IRB) approval, patients discharged from Baystate Medical Center with IE documented by modified Duke criteria treated with OPAT were identified. Data obtained included organisms implicated, indications of clinical stability, percentage of total…

Posted in: antibiotics 6 infective endocarditis 2
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