Review

Staphylococcus lugdunensis: An Emerging Pathogen

Objective: To evaluate the clinical relevance and impact of an emerging bacterial pathogen, Staphylococcus lugdunensis, in a large teaching hospital. Methods: Three-year retrospective microbiological and clinical review of all S. lugdunensis isolates from a single medical center. Results: Seventy-seven isolates were identified; 70 had complete data. Soft tissue, bone, joint,…

Posted in: endocarditis 8 osteomyelitis 11

Case Report

Subcutaneous Abscess in the Lower Leg Caused by BCG-Related Osteomyelitis

We report an unusual case of tibial osteomyelitis resulting from Bacille Calmette-Guerin vaccination and causing subsequent cortical destruction and a subcutaneous abscess. A 10-month-old infant initially presented with a tender palpable mass below the left knee. Radiographs showed an osteolytic lesion in the proximal metaphysis of the tibia. Magnetic resonance…

Posted in: abscess 6 Calmette-Guerin 2 osteomyelitis 11 subcutaneous 2 vaccination 11

Case Report

Sternal Osteomyelitis After Minor Trauma

Abstract:Sternal osteomyelitis secondary to minor trauma occurs rarely. Only a handful of cases have been reported. A 24-year-old male patient who had history of intravenous drug abuse and recent minor sternal trauma presented with signs and symptoms of sternal infection. Imaging studies suggested osteomyelitis and the patient underwent sternal resection,…

Posted in: osteomyelitis 11 Staphylococcus aureus 14 surgery 23

Case Report

Multidrug-Resistant Viridans Streptococcus (MDRVS) Osteomyelitis of the Mandible Successfully Treated with Moxifloxacin

Multidrug-resistant viridans group streptococcus (MDRVS) strains have emerged as important pathogens. Treatment of MDRVS infections is problematic. The use of fluoroquinolones for treatment of MDRVS osteomyelitis has not been established. We present the first case of MDRVS osteomyelitis of the mandible successfully treated with sequential intravenous then oral moxifloxacin, and…

Posted in: mandible 2 moxifloxacin 2 osteomyelitis 11

Case Report

Osteomyelitis Concurrently Caused by Staphylococcus aureus and Mycobacterium tuberculosis

We report the case of a 59-year-old woman who presented with fever and a cutaneous ulcer on her left ankle. In addition to Staphylococcus aureus growth from a blood culture, S aureus and Mycobacterium tuberculosis were both isolated from tissue specimens. This case highlights that osteomyelitis may be concurrently caused…

Posted in: Mycobacterium tuberculosis 4 osteomyelitis 11 Staphylococcus aureus 14

Original Article

Blastomycosis of Bones and Joints

A retrospective study of 45 patients hospitalized with blastomycosis of bones or joints revealed 41 cases of osteomyelitis and 12 cases of septic arthritis. The majority were men (35 [78%] patients) and non-Aboriginal (32 [71%] patients). Median time from the onset of symptoms to hospitalization was shorter in women than…

Posted in: osteomyelitis 11 septic arthritis 6

Case Report

Cryptococcal Osteomyelitis of the Humeral Head Initially Diagnosed as Avascular Necrosis

Cryptococcal skeletal infections can lead to significant morbidity and mortality and should be considered in the differential diagnosis of lytic osseous lesions. Clinical and radiological similarities to various disorders may lead to delay in initiation of antifungal treatment. This report describes a case of cryptococcal osteomyelitis of humeral bone in…

Posted in: Cryptococcus 2 osteomyelitis 11

Case Report

Idiopathic Osteomyelitis at the Base of the Skull

Osteomyelitis of the skull base is a rare disorder, and even more so when the etiology is noninfectious. Symptoms are noisome and include headache and cranial nerve deficits. Because of the possibility of neoplasia, thorough evaluation, accurate diagnosis, and effective treatment are mandatory. In the case reported herein, a 58-year-old…

Posted in: osteomyelitis 11

Case Report

Ceftriaxone-resistant Salmonella Septicemia and Osteomyelitis in Sickle Cell Disease Adults

Abstract:The majority of data evaluating Salmonella infections in sickle cell anemia (SCD) comes from studies performed in children. We report a SCD adult who presented with ceftriaxone-resistant Salmonella bacteremia. After appropriate initial therapy, persistent back pain prompted evaluation by magnetic resonance imaging of the spine, which revealed osteomyelitis and a…

Posted in: bacteremia 10 hemoglobinopathies 3 osteomyelitis 11 Salmonella 2 sickle cell 4

Case Report

Disseminated Cat Scratch Disease With Vertebral Osteomyelitis and Epidural Abscess

A 5-year-old boy with cat scratch disease presented with fever of unknown origin and osteomyelitis of the thoracic spine and epidural abscess. He did not have localizing signs or symptoms. Computed tomography of the abdomen, which was initially negative, showed hepatosplenic disease. Cat scratch disease has variable systemic presentations and…

Posted in: epidural abscess 2 osteomyelitis 11

Case Report

Mycobacterium Tuberculosis Infection of a Presumed Charcot Joint

A 65-year-old male with peripheral neuropathy and small lymphocytic lymphoma presented with erythema and edema of the left foot. A Charcot midfoot was diagnosed and treated with a total contact cast and restricted weight bearing. However, subsequent analysis of bone and synovial fluid months later revealed Mycobacterium tuberculosis infection. Key…

Posted in: Mycobacterium tuberculosis 4 osteomyelitis 11
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